Background Diffusion-tensor imaging (DTI) is a magnetic resonance imaging (MRI) technique that depicts the integrity of white matter (WM) tracts. This study was conducted to assess the utility of DTI tractography as an imaging technique in assessment of brain gliomas and planning of the surgical corridor. Results Twenty adult patients with brain gliomas were included. Neurological examination and conventional MRI and DTI scans were performed before and after surgery. Low-grade and high-grade tumors were found in 30% and 70% of patients, respectively. Preoperative DTI demonstrated five patterns of WM tract involvement: non-affected (10%), displaced (75%), edematous (55%), infiltrated (60%), and disrupted (20%). The obtained DTI scans were used for preoperative planning of the surgical corridor and extent of resection to achieve the maximum resection while preserving the WM tracts. Total resection was achieved in 40%, while 60% underwent subtotal resection. Postoperative neurological examination showed deterioration of cognitive function, motor power, and vision in 15%, 10%, and 5% of patients, respectively. Headache persisted in 15%, while motor power improved in 35% of patients. High-grade tumors were significantly associated with higher percentage of subtotal resection (p=0.018) and pattern IV (p=0.018). There was a significant association between the preoperative pattern of WM tract involvement and the postoperative DTI changes (p<0.001). Conclusion DTI enables assessment of displaced and infiltrated WM tracts in the vicinity of brain tumors. Preoperative planning of tumor resection and surgical corridor should include DTI scan to achieve the balance between maximum resection of tumor and maximal preservation of function.

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The olfactory bulb is characterised by neural plasticity, and its volume may be affected by the peripheral olfactory function.

Background In this study, we combined ultrasound and Doppler parameters to conclude the most accurate and applicable method for fetal lung maturity assessment. Thepurpose is to reduce risk of neonatal respiratory distress by assessment of fetal lung maturity through ultrasound and Doppler instead of amniocentesis. Results A total of 120 women were included. The ultrasound examination was performed at a gestational age ranging between 30 and 37 weeks and delivery occurred within 72 h from ultrasound. After birth, 19 fetuses were diagnosed with RDS. The ultrasound parameters assessed for fetal lung maturity showed varying sensitivity and specificity but presence of proximal tibial epiphyses showed the highest sensitivity (91%) and specificity (95%) followed by the presence of distal femoral epiphyses with 90% sensitivity and 84% specificity. The placental grade III maturity showed a sensitivity of 81% and 74% specificity followed by the presence of the amniotic fluid free-floating particles with an 83% sensitivity and 63% specificity, while echogenic fetal thalamus showed 77% and 79% for sensitivity and specificity, respectively, for prediction of fetal lung maturity. By using the fetal biometry, we could report that a BPD between 82.8 and 93.5 mm, AC between 295 and 322 mm, and FL (62.7-72.1 mm) correlated with mature fetal lungs. Regarding Doppler indices, increased resistive index of umbilical artery > 0.69 and of pulmonary artery > 0.78 correlated with neonatal RDS while fetuses with UtA RI values between 0.43 and 0.66 noticed in RDS vs (0.42-0.57) in the non-RDS. MCA RI values are also higher in RDS 0.77–0.88 vs 0.74–0.79 in non-RDS. On the other hand, analysis of colon grading and fetal lung echogenicity in relation to liver showed no significant value in the assessment of fetal lung maturity. Conclusion Ultrasound and Doppler showed good predictive value and accuracy and is considered a valuable non-invasive procedure in assessment of fetal lung maturity. However, no single parameter alone could show a definitive sign