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The present study focused on the green synthesis of biocompatible, nano-sized AM-AgNP, from Atalantia monophylla aqueous leaf extract, with significant biomedical applications.Surface Plasmon Resonance (SPR) of AM-AgNP recorded at 396 nm wavelength at an optimum 12 pH and the impeccable intensity of emission peak obtained at 513 nm of PL spectra at 400 nm excitation wavelength, endorsed better synthesis and maximum quantum yield respectively. AM-AgNP atom arrangement exhibited face centred cubic (FCC) type, with an average crystal size of 8.3 nm and when combined, formed a polycrystalline particle size of 11.3 nm, as calculated by Scherer's formula using XRD data, HR-TEM micrograph and SAED pattern respectively. Biocompatible silver nanoparticles have shown selective antimicrobial activity against gram-positive and gram-negative bacterial strains. Green synthesized AM-AgNPs have shown significant in-vitro removal of DPPH and ABTS free radicals compared to aqueous A. monophylla leaf extract and Gallic acid standard. Cell cytotoxicity of AM-AgNP was evaluated against normal (immortal) human embryonic kidney (HEK 293) cell lines and human cervical cancer (HeLa) cell lines that revealed dose dependant, selective cell cytotoxicity besides biocompatible properties.

A silver/zinc oxide nanocomposite (Ag/ZnONC) was synthesized using the aqueous leaf extract of Atalantia monophylla as a reducing and capping agent, under controlled and effective microwave heating with silver nitrate (AgNO 3 ) and zinc nitrate hexahydrate (ZnNO 3 Á6H 2 O) serving as precursor salts. The X-ray diffraction spectra peak and selective area electron diffraction patterns confirmed the crystalline nature of the synthesized nanocomposite particles. High-resolution scanning electron microscopy images and high-resolution transmission electron microscopy micrographs of Ag/ZnONC showed an aggregated net-like structure containing small spherical Ag nanoparticles (AgNPs) supported by the large aggregated ZnO nanoparticles (ZnONPs). The eco-friendly synthesized Ag/ZnONC shows great relevance in areas like photonics, catalysis, electronics, and biomedicals.

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The facile and rapid biosynthesis of copper oxide nanoparticles (AM-CuONPs) using Atalantia monophylla leaves extract under microwave irradiation is investigated. Optical and structural characterizations confirm the synthesis of spherical to rod-shaped phase pure AM-CuONPs. The antibacterial activity of AM-CuONPs is higher with Gram-positive bacteria compared to Gram-negative bacteria. The antioxidant potential of AM-CuONPs is reflected in radical scavenging activities in a concentration-dependent manner, tested by 2,2-diphenyl-1picrylhydrazyl and 3-ethylenebenzothiazoline-6-sulfonic acid diammonium salt assay. The promising anticancer activity of AM-CuONPs is observed by killing 80 % of HeLa cells without affecting normal human embryonic kidney cells. The results reveal the potential of biosynthesized AM-CuONPs for antibacterial, antioxidant, and anticancer applications.