To explore the antibacterial activities of Allium sativium (garlic) extract was tested against two waterborne pathogenic strains isolated from River Nile, to mitigate the increase of bacterial resistance to conventional antibiotics. The two isolates were identified as Enterobacter cloacae DSM 3264 BRB & Enterobacter cloacae MB11506_1CHB by MALDI-Tof-MS. Aqueous, methanolic and oil extraction of garlic were tested for their inhibitory activity against the selected strains using well diffusion method. Enterobacter sp. were more sensitive towards oil extract with inhibition zone 2.3 cm rather than aqueous and methanolic extractions with was 50%. Analysis of garlic essential oil by GC-MS dedicated six sulfur compounds represented 25% of total detected compounds in the oil.
Purpose: to evaluate the antibacterial effect of Nutmeg natural extract on cariogenic microflora and compare its effect with chlorhexidine (CHX) in a group of Egyptian children. Subject and methods: A total of 60 normal apparently healthy children aged between 6-12 years from both genders were involved in this study and equally divided into two groups (n=30) regarding to the type of the received mouthwash: group 1; included children who rinsed with 1% Nutmeg extract containing mouth wash (Tested group); group 2; included children who rinsed with 0.12% CHX containing mouth wash (Control group). Saliva samples were collected from each enrolled child at the baseline (before the use of mouthwash), and at 7 th day after the use of mouthwash. Mitis salivarius bacitracin and Rogosa agar media were used to determine Streptococcus mutans (S. mutans) and Lactobacilli count respectively. Results: Significant reduction in S. mutans and Lactobacilli count in the two studied groups after mouth rinsing for 7 days. However, CHX showed a significant reduction in S. mutans and Lactobacilli count when compared to Nutmeg extract. Conclusions: Nutmeg extract has a significant positive antimicrobial effect against S. mutans and Lactobacilli microorganisms but the use of CHX mouthwash has a higher antimicrobial effect when compared to Nutmeg extract.
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