Antimicrobials are used to inhibit or fight the growth of certain microorganisms and, therefore, they are widely used in the intensive care unit. Pharmacoeconomics is used to improve the use of financial resources, taking the cost-effectiveness of treatment into account. The objective of this work was to analyze the consumption of antimicrobials, identifying the most expensive and most used, in addition to verifying the therapeutic class of greatest consumption. This is a retrospective study with a quantitative approach, carried out from January 2019 to May 2019 in a tertiary hospital. The data were obtained from the forms of use of restricted medications and the database of the hospital. These were recorded in a Microsoft Office Excel 2016® spreadsheet and the expense with antimicrobials was calculated by multiplying the number of units dispensed by the unit price in reais. The analysis of descriptive statistics occurred through the calculation of frequency and percentage. In the period analyzed, 10,286 units of antimicrobials were consumed, corresponding to a total cost of R$ 269,265.94 reais. The most expensive drugs were, respectively, piperacillin + tazobactam, meropenem and linezolid; the most consumed were meropenem, piperacillin + tazobactam and vancomycin, respectively. The classes with the highest consumption were, respectively, carbapenems, penicillin and glycopeptides. From the results, it was verified that the consumption of antimicrobials in the intensive care unit generates a high financial impact on the hospital, in addition to the fact that the most consumed antimicrobials that generated the highest costs were those of broad-spectrum.
Antimicrobials are one of the most widely prescribed classes of drugs worldwide. Due to the large number of occurrences of Health care-associated infections (HAIs), the most diverse classes of these drugs are used and this problem becomes more serious in the Intensive Care Unit (ICU), which is considered an ideal environment for HAIs. The main objective of this study was to analyze the profile of antimicrobial consumption in patients in the Intensive Care Unit of a state public hospital and the consequences of the use of these drugs on kidney function. It is a retrospective quantitative study, including only information contained in the database of patients admitted from January 1 to March 31, 2019, who consumed at least one antimicrobial. The data were recorded in Microsoft Excel spreadsheets and analyzed using relative and absolute frequencies. A higher consumption of carbapenems and a higher prevalence of the microorganism Acinetobacter baumannii were observed, which confirms its rapid dissemination. 46.94% of the patients had impaired kidney functions. In view of this, the importance of a pharmacist in the ICU is demonstrated as he contributes to the review of pharmacotherapy, besides assisting with strategies in choosing the right antimicrobials at doses tolerated by the patient.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.