This population-based study demonstrated an increase in the incidence of nonmelanoma skin cancer among young women and men residing in Olmsted County, Minnesota. There was a disproportionate increase in basal cell carcinoma in young women. This increase may lead to an exponential increase in the overall occurrence of nonmelanoma skin cancers over time as this population ages, which emphasizes the need to focus on skin cancer prevention in young adults.
Mohs micrographic surgery compares favorably with wide excision. Intraoperative immunostaining with cytokeratin 7 is helpful in delineating disease, as are preoperative scouting biopsies and photodynamic diagnosis.
Analysis of 1,620 basal cell carcinomas treated at the Cleveland Clinic Foundation from 1981 to 1983 confirms that the majority of basal cell carcinomas occur on the face and that the relative risk for recurrent tumor is high in certain locations, especially the nose. Alternately, tumors found on the neck/scalp, trunk, and arms have a low relative risk of recurrence when compared to all other anatomic locations. More primary and fewer recurrent tumors now presenting to our unit have been referred for Mohs surgery as primary therapy. This results in higher cure rates for treatment of all basal cell carcinoma.
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