Background: Neuroinflammation has been implicated in the pathogenesis or the progression of the variety of acute and chronic neurological and neurodegenerative disorders including Alzheimer's disease.
Acrokeratoses verruciformis of HOPF (AKV) is a rare Genodermatoses presenting as multiple plane wart-like lesions symmetrically distributed on dorsum of hands and feet. Its pathogenesis is unknown. A case of 45 years old male is described with warty papules and plaques on dorsa of hands since 3 years with similar lesions on nape of neck and anterior aspect of chest with erythematous plaque in a butterfly distribution over the face. With history of photosensitivity. Histopathology showed changes of AKV. We are reporting unusual association of AKV with polymorphic light eruption (PLE).
BACKGROUND AND OBJECTIVES: Skin tags (Acrochordons) are very common benign tumor of the skin. It is seen in 25% of population, particularly in women in advancing age and in pregnancy. Skin tags are small, soft, pedunculated and papillomatous lesions usually seen on eyelids and major flexures of the body. Skin tags are entirely asymptomatic and diagnosis is unmistakable. Many cutaneous lesions have been well established to be associated with some systemic diseases and this has been proven beneficial as it helps in early diagnosis. METHODS: A total no of 50 patients with skin tags were included in the study. Detailed history, thorough physical examination and relevant investigations were done to confirm the systemic manifestations when present. RESULTS: In the study the patient's age ranged from 18-65 yrs with female -male ratio 1:1.17. The number of skin tags among the 50 patients ranged from 1-74. In our study we found that 74% of our patients with skin tags were either obese or overweight, 24% of our patients fulfilled the criteria of metabolic syndrome,
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.