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The free radicals play vital role in induction of various diseases. Natural antioxidants may help the body to protect itself from various types of oxidative damage which are linked to diseases such as cancer, diabetes, cardiovascular disorders and aging. Martynia annua belonging to

: Nanotheranostics, an approach of combining both diagnosis and therapy, is one of the latest advances in cancer therapy particularly. Nanocarriers designed and derived from inorganic materials such as like gold nanoparticles, silica nanoparticles, magnetic nanoparticles and carbon nanotubes have been explored for tremendous applications in this area. Similarly, nanoparticles composed of some organic material alone or in combination with inorganic nano-cargos have been developed pre-clinically and possess excellent features desired. Photo-thermal therapy, MRI, simultaneous imaging and delivery, combination chemotherapy with diagnosis are a few of the known methods exploring cancer therapy and detection as organ/tissue/molecular/sub-cellular level as well. This review comprises an overview of the recent reports meant for nanotheranostics purposes. Targeted cancer nanotheranostics have been included for understating tumor microenvironment or cell specific targeting approach employed. A brief account of various strategies is also included for the readers highlighting mechanism of cancer therapy.

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Curcuma caesia is commonly known as kali haldi and it belongs to the family Zingiberaceae.  Black turmeric is an uncommon endemic as well as ethno medicinally important of South East Asia. This herb is available throughout north-east, central India, Papi Hills of East Godavari, West Godavari, and Andhra Pradesh. In the traditional system of medicine, fresh and dried rhizomes of Curcuma caesia are used in treating leucoderma, asthma, tumours, piles, bronchitis, bruises etc. Curcuma caesia has scientifically studied for various therapeutical activities like antioxidant, antibacterial, antipyretic, larvicidal, insecticidal, antimicrobial, wound healing and anti-hyperglycaemic. The present review is an effort to give a detailed survey of the literature on its, phytochemistry, traditional uses and therapeutical studies.

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Martynia annua belongs to family Martyniaceae is an herbaceous annual plant, spread throughout India. It is commonly known as the Cat's claw or Devil’s claw. In India, traditional healers used M. annua in the treatment of epilepsy, inflammation, sore throat, burns, itching, skin affections and tuberculosis. M. annua contains alkaloids, tannins, saponins, glycosides, flavonoids, anthocyanins, amino acid, steroids and phenols. The researcher scientifically documented various pharmacological activities such as anthelmintic, analgesic, antipyretic, antibacterial, anti convulsant, antifertility, antinociceptive, antioxidant, CNS depressant, antidiabetic and wound healing activity of this plant. The reported activities make the plant in great interest among scholars to determine the mechanism of pharmacological activities of crude extracts. Hence the review paper outlines the previous research done on M. annua.

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