Catalyst efficacy of in situ generated Pd-nanoparticles in the regioselective one-pot synthesis of substituted pyrazoles and isoxazoles via sequential coupling-cyclization methodology in environmentally benign medium is described.
A new series of pyrazoline-steroidal diglycoside hybrids were synthesized via catalyzed cyclocondensation of the corresponding chalcones, screened for in vitro cytotoxic activity and the SAR deduced.
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