Aims and Objectives: The aim of the study was to assess and compare the effect of smoking on mRNA expression of MMP -8 and TIMP-1 in patients with untreated chronic periodontitis and in periodontally healthy subjects and to examine the correlation of MMP-8 and TIMP-1 levels with clinical parameters. Materials and Methods:Out of 60 subjects, 40 were selected subjects for the study, and were divided into Group I (periodontitis subject) and Group II (healthy subjects). Each group was further subdivided into subgroups I-A (chronic periodontitis smokers CPS), and I-B (chronic periodontitis non-smokers CPN), subgroup II-A (healthy smokers HS) and II B (healthy non-smokers HS). Both the groups underwent periodontal examination and clinical parameters were recorded. Tissue samples from both groups were subjected to the isolation of RNA which was then followed by qRT-PCR and the expression of the mRNA levels of MMP-8 and TIMP-1 were analyzed.
The utilisation of medical device e.g. an infusion pump is commonly treated as non-trivial process in service and maintenance section albeit in actuality, it is a crucial process for determining its correct maintenance cycle. Therefore, a discussion on the capability of magnetometer sensor as one of potential sensors to be used to keep track the utilisation status of infusion pump. The variation of magnetic flux density and its frequency produced by the stepper motor inside the infusion pump is measured and analysed through magnetometer sensor, embedded inside a Bluetooth Low Energy (BLE) device. Obtained result shows that magnetometer sensor has the potential to track the utilisation status of the tested infusion pumps.
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