Objective To determine whether an isolated echogenic intracardiac focus in the fetal heart in the mid-trimester (16-24 weeks)

Objectives: To determine the correlation between cytology, colposcopy and histopathology, individually and in combination, in high-risk patients for detection of early cancer of the cervix. Materials and methods:A total of 200 high-risk patients in the age groups of 35 to 60 years were included in the study. Pap smear, colposcopy and colposcopically directed biopsies were taken from the suspicious area.Results: Sensitivity, specificity and positive predictive value of Pap smear are 65.2, 96.3 and 89.3% respectively. Correlation between cytology and colposcopy was 81%, between colposcopy and histopathology was 90.6%, between cytology, colposcopy and histopathology was 90.6% and between cytology, colposcopy and histopathology was 87.3%. Conclusion:Combination of various methods increases the diagnostic accuracy over that of each method separately.

Objective Comparison of oral and vaginal administration of lowdose misoprostol for induction of labor at term. Materials and methods Two hundred pregnant women after 37 weeks of gestation with an indication for induction were given 25 μg of misoprostol orally (study group) or vaginally (control group), every 3 hours to a maximum of 8 doses. The induction to delivery interval, requirement of oxytocin, dose of misoprostol used, maternal and neonatal outcome were analyzed statistically. Results The median induction to delivery interval was significantly shorter in those induced with vaginal misoprostol (p = 0.06). The median induction to delivery interval was 21.35 ± 7.44 hours in study group and 14.64 ± 5.49 hours in control group. Eighty-two percent women in study group and 84% women in control group had vaginal delivery. Cesarean section rate was lower in control group, 16% vs 18% in study group, but the difference was not statistically significant (p = 0.790). Oxytocin augmentation was needed for 80% cases in the study group and 54% cases in control group, which was statistically significant (p = 0.006). The incidence of abnormal FHR was more in control group as compared to study group (30 vs 14%). Hyperstimulation syndrome was observed in 4% cases in control group and 2% cases in study group. Neonatal outcome was found to be similar in both groups. Conclusion Vaginal misoprostol achieved higher success rate within a short induction interval but was associated with increase in abnormal FHR pattern and abnormal uterine activity as compared to the oral route. Oral route had comparable efficacy, was safe and well-tolerated route of misoprostol administration for induction of labor at term. How to cite this article Mahajan M, Gupta KB, Sharma R, Jyoti R. Comparison of Oral and Vaginal Administration of Low-dose Misoprostol for Labor Induction. J South Asian Feder Obst Gynae 2012;4(3):137-140.

Cantrell's pentalogy with ectopia cordis is an extremely rare and lethal congenital anomaly. We discuss the case and present a brief review of literature of embryogenesis.