Acne fulminans is a rare condition and the most severe form of acne. It involves the sudden onset of febrile and multisystemic symptoms, with poor response to ordinary therapy in patients who previously had mild to moderate acne. It is characterized by hemorrhagic ulcerative crusting lesions on the face, chest and upper back. The authors report a case of acne fulminans that was successfully treated with oral prednisone and dapsone.
About 24.7% of women in the sample never had a mammography. According to the findings, the lack of breast cancer screening is associated with social and racial inequalities.
BACKGROUND While representing only 3-4% of malignant skin tumors, cutaneous melanoma is the
most aggressive and lethal. Statistical knowledge about the biological behavior of
this tumor is essential for guiding daily outpatient practice and aiding public
health policies. OBJECTIVES To analyze the profile of patients with cutaneous melanoma attending a pathology
department in Teresina (state of Piauí) between 2000 and 2010. METHODS Retrospective study of melanoma patients diagnosed between 2000 and 2010 in the
São Marcos Hospital in the city of Teresina. The pathology laboratory reports were
studied and all the statistical analyses performed using SPSS 19.0. RESULTS A total of 25 in situ, 199 invasive and 89 metastatic melanomas of unknown
primary site were observed. Histological types found were nodular (52.8%),
superficial spreading melanoma (18.6%), acral (10.6%) and lentigo maligna (9.5%).
In 144 (73.4%) cases the Breslow thickness was >1 mm. Metastasis was found in
28.6% of invasive melanomas and nodular melanoma, Clark IV/ V, Breslow > 1 mm,
mitotic index ≥ 6 and ulcerated lesions were more likely to metastasize. CONCLUSION Most melanomas presented Breslow> 1mm. The main factors associated with
metastasis were nodular type, Clark IV / V, Breslow> 1mm, mitotic index ≥ 6
and ulcerated lesions.
A incidência do melanoma cutâneo é crescente em todo o mundo. A presença de metástases em linfonodos é o mais importante fator prognóstico, sendo que a probabilidade de envolvimento linfonodal é maior nas lesões de maior espessura, ocorrendo em 20% dos pacientes com Breslow, de 1 a 4mm. A pesquisa do linfonodo sentinela já é padrão em melanoma e representou um avanço no tratamento da doença, por evitar linfonodectomias radicais desnecessárias, diminuindo a morbidade do tratamento. Apresentamos uma série de casos de pesquisa de linfonodo sentinela em pacientes com melanoma, em Teresina-Piauí, nos anos de 2008 e 2009.
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