One of a synthetic food dye which used worldwide is Tartrazine, it is an orange-colored, water soluble with a potential toxicological risk. Food or drinks containing tartrazine caused sensitivity symptoms. Vitamin E is an essential lipid-soluble vitamin and has well-established antioxidant properties which improve the proliferation, differentiation, and mineralization, and reduced apoptosis of osteoblastic cells.Aim of this study: to evaluate the effect of tartrazine and co-administration of vitamin E on post extraction socket using histological examination by light microscope.
Materials and methods:Surgical extraction of mandibular first molars were done in a twenty one albino rats, the animals were randomly divided into 3 groups; group I (control), group II given tartrazine and group III given tartrazine and Vitamin E (treated group).
Introduction: Cementodentinal junction (CDJ) is the interface between cementum and dentin. The cause of this attachment was described by the intermingling of cemental and dentinal fibers or the accumulation of adhesive proteoglycans at the cementodentinal junction. Cementum was classified to three major types according to the type of fibers; Acellular extrinsic fiber cementum, Cellular intrinsic fiber cementum and Cellular mixed stratified cementum.
Aim of Work:To observe the cemento-dentinal junction in human mandibular deciduous 2 nd molar and mandibular permanent 1 st molar by scanning electron microscopy combined by NaOH maceration. Materials and Methods: Twenty extracted mandibular deciduous 2 nd molar and mandibular permanent 1 st molar with complete root(s), were collected. The teeth preserved in 10% formalin then divided into two groups consisted of 10 teeth each. All teeth were cut mesiodistally into halves with a diamond desk, then the sectioned halves were demineralized by formic acid 10% for one month then were immersed in 10% NaOH aqueous solution for 2-3 days at room temperature and rinsed in distilled water overnight (24 hours). Results: Acellular cementum in mandibular deciduous 2 nd molars showed a gap with complete separation, while in cellular cementum there is fibril poor gap and fibril intermingling between the intrinsic fibers of cellular cementum and dentin root fibers. The gap and the intermingling fibers were not observed in the examination of cellular cementum in mandibular permanent 1 st molars while in acellular cementum there is a fiber intermingling observed. Conclusion: Fibril intermingling plays a role in cementum to dentin attachment.
Purpose: The purpose of this study was to evaluate the effect of combining the PRGF to Xenograft on quality of the newly formed bone in open sinus lifting procedures after six months. Patients and methods: Thirty maxillary sinuses were augmented in twenty five patients, 18 males and 7 females, who had less than 5 mm of bone height. Maxillary sinuses were randomly allocated into one of three groups; the study group I, where the sinus was augmented using autogenous bone taken from the patient's chin, group II, in which the sinus was augmented using Xenograft mixed with saline, group III, in which the sinus was augmented using Xenograft mixed with Platelets rich in growth factors (PRGF). After 6 months healing period, core biopsies were harvested and implant was simultaneously placed in the same site. Comparative microscopic and histomorphometric analysis were conducted and statistically analyzed. Implant loading was done after 6 months healing period. Results: After 6 months, the results of this study showed that there was no adverse effect noticed in any case during the follow-up period. Histological findings showed that the addition of PRGF promotes bone maturation preceding the bovine grafted material alone. The histological stained specimens of group III revealed a picture more or less resembling group I (autogenous bone). The amount of the residual graft particles in the group I and III were found to be less than group II. Conclusion: Combining PRGF to the xenograft improved the handling characteristics and the quality of the bone after 6 months in maxillary sinus augmentation procedure. Although PRGF combined to xenograft promoted bone maturation preceding the bovine grafted material alone, it did not prove to be superior to the autogenous bone which remains to be the gold standard for grafting.
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