In the present work we found that faster progression to the mild DLB stage in the first few years of the disease is mainly related to deterioration of memory, attention/executive functions, and visuospatial abilities, as well as an increased frequency of visual hallucinations.

The data suggest a role of the APOE genotype as a disease-modifying factor.

Darier Disease (DD), or keratosis follicularis, is an uncommon, slowly progressive, autosomal-dominant skin disorder. DD is characterized clinically by multiple keratotic papules and histological finding shows loss of adhesion between epidermal cells and abnormal keratinization. Citation: Pehlivanov G, Traykovich NT, Bakardzhiev I, Pavlova R, Balabanova M, et al. (2016) Darier Disease following Blaschko Lines-Case Report. Clin Res Dermatol Open Access 3(6): 1-2.