Background: Relationship between thyroid hormones and lipid profiles in patients with struma is a common condition found in IDD endemic areas.Objective: This study observes relationships between thyroid functions and lipid profiles in woman patients of childbearing age with struma. Methods: This paper is a cross-sectional study of 83 subjects/patients who met inclusion and exclusion criteria in this study. Total cholesterol, LDL, HDL, TSH, and free T4 concentration were measured in all the patients. Lipid concentrations in patients with thyroid dysfunction and patients with euthyroid were compared by using a linear regression model. Results: Total cholesterol, LDL, and HDL was significantly lower in patients with primary hyperthyroidism (N=19) than in patients with euthyroid (N=48) (mean±SD 122.8±20.09 mg/dl vs 187.3±33.66 mg/dl, p=0.000 unadjusted, p= 0.000 adjusted for age and BMI); (63.5±16.33 mg/dl vs 121.7±29.71 mg/dl, p=0.000 unadjusted, p= 0.000 adjusted for age and BMI); (48.8±9.66 mg/dl vs 53.6±8.49 mg/dl, P=0.049 unadjusted, p=0.026 adjusted for age and BMI. Serum total cholesterol and LDL was lower in patients with subclinical hyperthyroidism (N= 14) than in patients with euthyroid (N=48), but it was not statistically significant (181.6±32.07 mg/dl vs 187.3±33.66 mg/dl, p=0.577 unadjusted, P=0.719 adjusted for age and BMI); (110.5±14.83 mg/dl vs 121.7±29.71 mg/ dl, p=0.181 unadjusted, p=0.250 adjusted for age and BMI). Serum HDL was similarly elevated in patiemts with subclinical hypothyroidism (N=14) than in patients with euthyroid (N=48), but it was not statistically significant (57.4±11.04 mg/dl vs 53.6±8.49 mg/dl, p=0.185 unadjusted, p=0.229 adjusted for age and BMI). Conclusion: Serum total cholesterol, LDL and HDL was significantly lower in patients with primary hyperthyroidism, but it was not significant for subclinical hyperthyroidism. Latar Belakang: Hubungan antara hormon tiroid dan profil lipid pada pasien struma menarik untuk dikaji karena struma adalah kondisi yang biasa ditemui pada daerah endemis gangguan akibat kekurangan iodium (GAKI) dan hal tersebut belum banyak diteliti. Tujuan: Penelitian ini melihat hubungan fungsi tiroid dan profil lipid pada pasien struma wanita usia subur di klinik litbang GAKI. Metode: Penelitian observasional potong lintang pada 83 subyek yang memenuhi kriteria inklusi dan
Stunting is one of the chronic nutritional problems in which the length or height of children is shorter than normal children their age. In the short term, stunting can interfere with brain and physical development, while in the long term, stunting can reduce a person's cognitive abilities and intelligence, as well as being susceptible to various diseases. Stunting cannot be cured, but it can be optimized for growth and development during the 1000 first days (first day of life) by routinely carrying out examinations. This is the goal of this study, namely to build a system that can monitor the health of pregnant women and toddlers aged 0-24 months in an effort to optimize the growth and development of stunting children. Stunting management monitoring system is carried out based on certain nutritional status management which indicates the birth of a child experiencing stunting. The system is built in the form of a website, where expert rules related to the management of nutritional status are translated into the system using the Rule Based Reasoning method. To measure the success of the system, usability testing or functional testing by users is carried out with the attributes of testing the ease of use of the system and the ease of the system to learn. Overall, the Stunting management monitoring system can accommodate the early stages of health monitoring in 1000 first days, however, development will continue in line with user needs.
ARTICLE INFOEffects of methanol extracts of insulin leaves (Tithonia diversifolia (hemsl.) A. Gray) on insulin resistance and secretion of alloxan induced-obese diabetic rats
Yoga merupakan salah satu aktivitas fisik yang menggunakan berbagai postur untuk mengembangkan kekuatan fisik, kelenturan dan ketahanan dimana dapat digunakan sebagai latihan berintensitas sedang untuk pasien dengan kapasitas latihan terbatas sehingga lebih mudah bagi orang-orang yang inaktif secara fisik. Tujuan Penelitian yaitu untuk mengetahui pengaruh yoga terhadap waist hip ratio (WHR) pada wanita di Desa Lodadi Kecamatan Ngemplak Kabupaten Sleman Yogyakarta. Penelitian ini merupakan penelitian pre–eksperimental dengan One Group Pretest - Postest Design. Subyek penelitian diperoleh dengan teknik purposive sampling di Desa Lodadi. Subyek berjumlah 30 orang. Yoga dilakukan sejak November 2018 hingga Januari 2019 setiap 2x seminggu selama 90 menit. WHR diukur dengan menggunakan meter ukur. Setelah itu data akan dianalisis dengan paired sample t-test. Hasil Penelitian menunjukkan dari 30 subyek penelitian 17 peserta termasuk dalam kriteria eksklusi. Hasil analisis statistik paired sample t-test didapatkan p<0,05 yang menunjukkan perbedaan bermakna antara WHR peserta sebelum dan sesudah pelaksanaan yoga. Kesimpulan pada penelitian ini adalah Yoga dapat mempengaruhi waist hip ratio pada wanita di Desa Lodadi Kecamatan Ngemplak Kabupaten Sleman Yogyakarta.
Latar Belakang: Berat badan lahir rendah masih menjadi penyebab kesakitan dan kematian pada bayi baru lahir. Kejadian bayi berat badan lahir rendah mencapai sekitar 20 juta kelahiran pertahun di seluruh dunia. Faktor risiko kejadian bayi berat badan lahir rendah antara lain usia ibu, hipertensi, umur kehamilan, jenis kelamin, paritas, jarak kehamilan, dan pendidikan ibu. Gunung Kidul pada tahun 2018 menjadi kabupaten dengan angka prevalensi tertinggi di Provinsi Daerah Istimewa Yogyakarta. Berdasarkan latar belakang, perlu dilakukan analisis mengenai faktor risiko kejadian bayi berat badan lahir rendah di RSUD Wonosari tahun 20z19Tujuan Penelitian: Mengetahui faktor risiko bayi berat badan lahir rendah (BBLR) di RSUD Wonosari tahun 2019. Metode Penelitian: Penelitian ini merupakan studi analitik observasional dengan desain case-control yang menggunakan data sekunder rekam medis RSUD Wonosari tahun 2019 dengan teknik purposivel sampling dimana besar sampel sejumlah 100. Analisis data dilakukan secara univariat, bivariat dan multivariat.Hasil: Analisis bivariat memperoleh hasil usia ibu (p value 0.003, OR 3.881 CI 95% 1,561-9,650), hipertensi (p value 0.000 OR 5.091 CI 95% 2,091-12,396), umur kehamilan (p value 0.000 OR 38.500 CI 95% 4,921-301,195), jenis kelamin (p value 0.548 OR 1.272 CI 95% 0,580-2,790), paritas (p value 0.001 OR 3,768 CI 95% 1.647-8.620, jarak kehamilan (p value 0.002 OR 3.841 CI 95% 1.610-9.161). Analisis multivariat memperoleh hasil usia ibu kurang dari 20 dan lebih dari atau sama dengan 35 (p value 0.034, aOR 6.147 CI 95% 1.151-32.840), ibu menderita hipertensi (p value 0.001, aOR 13.255 CI 95% 2,986-58,842), umur kehamilan kurang dari 37 minggu (p value 0.002, aOR 36,473 CI 95% 3,666-362,839), paritas 1 dan lebih dari 4 (p value 0,049, aOR 4,316 CI 95%1,007-18,490), jarak kehamilan kurang dari atau sama dengan 24 bulan (p value 0,008, aOR 14,470 CI 95% 2,036-102,818), pendidikan di bawah SMA (p value 0,000, aOR 5 ,913 CI 95% 1,402-24,94). Kesimpulan: Terdapat hubungan antara usia ibu kurang dari 20 dan lebih dari 35 tahun, ibu yang menderita hipertensi, umur kehamilan kurang dari 37 minggu, paritas 1 dan lebih dari 4, jarak kehamilan kurang dari atau sama dengan 24 bulan, pendidikan ibu kurang dari SMA dengan kejadian bayi berat badan lahir rendah di RSUD Wonosari tahun 2019.
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