In this study, we present findings that detail the criminal offending histories and typologies of suspected sexual offenders identified from an initiative to follow up on the testing of thousands of previously untested sexual assault kits (SAKs). This study advances our understanding of sexual offenders by incorporating data from criminal justice system records (“detected” criminal offending) with data from newly tested SAKs that were not previously adjudicated (“undetected” sexual offending). Our findings demonstrate that these offenders have extensive criminal histories, very frequently continued to offend after the SAK-associated sexual assault, and, more often than not, have criminal histories that do not include a prior arrest(s) for rape. A latent class analysis identified three classes of offenders based on their offending history, “High-Volume Generalists,” “Low-Volume Offenders,” and “Sexual Specialists.” Most were generalists, with a large proportion committing lots of serious crimes.
Background-Serum levels of the astrocytic protein S100B have been reported to indicate disruption of the blood-brain barrier. In this study, we investigated the relationship between S100B levels and childhood trauma in a child psychiatric inpatient unit.Method-Levels of S100B were measured in a group of youth with mood disorders or psychosis with and without history of childhood trauma as well as in healthy controls. Study participants were 93 inpatient adolescents admitted with a diagnosis of psychosis (N = 67), or mood disorder (N = 26) and 22 healthy adolescents with no history of trauma or psychiatric illness. Childhood trauma was documented using the Life Events Checklist (LEC) and Adverse Child Experiences (ACE).Results-In a multivariate regression model, suicidality scores and trauma were the only two variables which were independently related to serum S100B levels. Patients with greater levels of childhood trauma had significantly higher S100B levels even after controlling for intensity of suicidal ideation. Patients with psychotic diagnoses and mood disorders did not significantly differ in their levels of S100B. Patients exposed to childhood trauma were significantly more likely to have elevated levels of S100B (p < .001) than patients without trauma, and patients with trauma had significantly higher S100B levels (p < .001) when compared to the control group. LEC (p 0.046), and BPRS-C suicidality scores (p = 0.001) significantly predicted S100B levels.Conclusions-Childhood trauma can potentially affect the integrity of the blood-brain barrier as indicated by associated increased S100B levels.
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