Our study found a positive association between father's involvement in maternal health and factors such as paternal education level, age, income level and father's attitude. Fathers' antenatal involvement was associated with paternal age and income level, while their perinatal involvement was associated with paternal age and education level. Our study on father's attitude toward presence at time of birth showed 83.8% compliance. Similarly, there was 67.1% compliance for presence during antenatal checkups.
We report a 52 year old patient presenting with a bladder stone formed over a migrated intrauterine device (Copper-T). Her history was pertinent for intrauterine contraceptive (IUCD) device placement 10 years back. Investigations included plain ultrasound of abdomen, X-ray of abdomen, urinalysis, and urine culture. Ultrasound and plain X-ray of the pelvis confirmed a bladder stone formed over a migrated copper-T intrauterine device. The device was removed through suprapubic cystolithotomy. Of all the reported cases of vesical stone formation over a migrated IUCD, this case is unique as the patient was an elderly - 52 year old - female. All previously reported cases are of younger age.
Objective The role of biomarkers in staging and grading periodontal disease has become detrimental in relation to the overall treatment plan. This study aimed at evaluating and comparing the role of sialic acid and IL10 in the early and moderate stages of periodontitis. Materials and Methods Patients were selected according to the assessment of pocket depth and radiographic bone loss. Bone loss was calculated as <15% for stage 1 and 15–33% for stage 2. Salivary samples were collected using spit technique 2 hrs post consumption of food. The unstimulated saliva was collected in a sterile graduated container every minute for 5–8 minutes. IL10 estimation was done using ELISA, and sialic acid estimation was done using the diphenylamine method. The variables for the three groups were assessed using ANOVA, and intragroup comparisons for quantitative data were evaluated using the post hoc Bonferroni test (P < 0.05). Results On comparing sialic acid levels among the three groups, stage 2 showed the highest mean (8.61) compared with the other two groups and was highly significant (P < 0.001). On the contrary, IL10 when compared to stage 1 and 2 periodontitis revealed insignificant change. Conclusion The value of IL10 was higher as patients progressed from health to periodontitis.
We report a 35 year old female patient referred to our ultrasound department to rule out congenital anomalies. The fetus was found to have a completely formed brain, base of the skull and facial structures but lacking a cranium. The fetus was therapeutically aborted. We correlated our antenatal sonographic findings with gross pathological features and CT Scan of the fetal head. Despite an extensive search, CT features of aborted fetal brain and base of skull were not found in the literature.
We report a case of diffuse abdominal hydatidosis with correlation of imaging findings with gross pathology. The patient had involvement of liver, diaphragm, pelvic cavity, ovary and abdominal wall. Hydatid cysts were morphologically different from each other including calcified, uniloculated and multiloculated cystic lesions. Our case is rare as ovary and abdominal wall involvement is described in less than 1 % cases of hydatid disease.
Metformin is a US FDA-approved oral anti-hyperglycemic medication used to treat non-insulin-dependent diabetes mellitus (NIDDM). Metformin, a biguanide drug, works by reducing glucose production in the liver, decreasing intestinal absorption, and improving insulin sensitivity, leading to lower blood glucose levels. Metformin is generally considered to be a medication with a good safety profile and high tolerability. However, metformin therapy is associated with an uncommon but potentially serious complication known as metformin-associated lactic acidosis (MALA), which is marked by severe lactic acid accumulation in the bloodstream. This case introduces an elderly female with multiple comorbidities who presented with confusion, malaise, and lethargy. Her laboratory findings revealed acute renal failure, severe metabolic acidosis, and significantly elevated lactic acid levels consistent with sepsis and possibly MALA. Aggressive resuscitation with fluids and sodium bicarbonate was initiated. Antimicrobial drugs were started for urinary tract infections. She subsequently required endotracheal intubation with invasive ventilation, pressor support, and continuous renal replacement therapy. Her condition gradually improved over several days. The patient ultimately recovered, and at the time of discharge, metformin was discontinued, and a sodium-glucose cotransporter-2 (SGLT-2) inhibitor was initiated. This case underscores the relevance of MALA as a potential complication of metformin therapy, particularly in patients with underlying kidney disease or other risk factors. Timely detection and prompt management of MALA can prevent progression to a critical stage and thus avoid potentially fatal outcomes.
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