Acute experiments on Nembutal-anesthetized (40 mg/kg, i.p.) white rats with extracellular recording and analysis of baseline spine activity of neurons in the fastigial nucleus of the cerebellum were performed in normal conditions and after exposure to vibration for 5, 10, and 15 days. The distribution of neurons in terms of the regularity and dynamics of spike flows and the modality of interspike interval histograms were determined, along with the mean neuron spike frequency and the coefficient of variation of interspike intervals. The results showed that the most significant changes in neuron activity in fastigial nucleus cells were formed during the first ten days of vibration. On day 15, there was a tendency for measures to return to control levels.
The background impulse activity (BIA) generated by neurons of the right lateral vestibular nucleus (LVN) of rats in the norm and under conditions of long-lasting general vibrational stimulation was subjected to computer analysis. Statistically significant changes in intragroup values of the mean BIA frequency were observed after 5 and 10 days with 2-h-long sessions of vibrational stimulation. Significant shifts in the distributions of LVN neurons by the level of regularity and dynamic types of BIA were observed 10 and 15 days with vibrational influences. Trends toward return of the intragroup mean value of the BIA frequency to the initial level were noticeable at the end of the stimulation period (15 days).
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