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The application of conventional cutting fluids as lubricants during machining operations is not user-friendly and eco-friendly. Owing to this reason, new eco-friendly and user-friendly alternatives to these cutting fluids are being extensively researched. In this context, the present work focuses on preparation of vegetable oil–based micro and nano cutting fluids, followed by evaluation of their applicability in machining. The comparative performance of micro and nano cutting fluids is consolidated and presented in this work. Micro and nano solid lubricants, namely, boric acid (H3BO3) and molybdenum disulphide (MoS2), are mixed with coconut and sesame oils separately and sonicated thoroughly. The samples thus prepared are used in machining for the examination of cutting forces, cutting temperatures, tool wear, and surface roughness in order to assess machining performance of the cutting fluid at the specific cutting conditions. It is observed that performance of nanofluids is better than micro fluids in reducing cutting temperatures, cutting forces, tool flank wear, and surface roughness of the machined surface.

In the beginning, conventional cutting fluids are used in machining process like turning and these leads to have better performance of machining. As cutting operation become severe the cutting fluid complexity increases. This is focused here on user friendly and ecofriendly cutting fluid use while machining. Machining with this type of fluids give better performance and better heat dissipation to protect tool and work piece from the overheating. From earlier research one of the options for that is coconut oil which is better above point of view and it's having higher thermal and oxidative properties. This coconut oil can be used with Nano particle which raise the heat carrying capacity while machining with hard material. Fluid mainly used in hard material machining like stainless steel, cooper etc. Main focus of this investigation will be on flank wear and surface roughness of work. In this work we also found that coconut oil having 0.5 % Nano boric acid suspended in coconut oil is suited best among the all experimental trial and having lower surface roughness and flank wear.

Carbamazepine was given to 152 patients who were receiving multiple drug therapy for uncontrolled seizures. The age range was 3 to 57 years. The mean average duration of epilepsy and carbamazepine therapy was 7.6 years and 19 months respectively. T h e conclusions are: (i) Carbamazepine is effective in reducing the multiple drug therapy while still maintaining better control of intractable epilepsy. (ii) Carbamazepine by reducing polypharmacy in epilepsy and probably by the relative lack of sedative action is effective in improving school o r work performances. (iii) Carbamazepine is a safe antiepileptic drug. K e y ~vords: Carbamazepineepilepsypolypharmacy. 0001-6314/81/640022-07 $02.5010 0 1981 Munksgaard, Copenhagen