Both RCM probes demonstrate high PPV. TWP-RCM shows higher NPV, since its broader field-of-view probably allows more exhaustive search for BCC criteria. The RCM criteria threshold for BCC identification should be further tested.
For clinically and dermoscopically equivocal small papules on curved facial surfaces, handheld RCM may be particularly helpful in differentiating benign lesions from skin cancer.
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