Objective-This study identified factors associated with remission from DSM-III-R alcohol dependence in an American Indian community group.Method-Participants were assessed using the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA).Results-Five hundred and eighty participants were assessed for alcohol use and alcohol use symptoms; 254 participants were found to have alcohol dependence. The rate of remission in this sample was 59%. Thirty-four percent of remitters and 39% of non-remitters had received treatment for alcohol problems. Remission from alcohol dependence was associated with being female, older, and married; an earlier age of onset of alcohol dependence; and self-reported depression symptoms from drinking. Absence of remission was associated with continuing to drink despite knowing one had medical problems from drinking and self-reported anxiety symptoms from drinking.Conclusion-Attention to factors associated with remission from alcohol dependence may be important in designing more effective treatment and prevention programs in this high risk population.

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