Factors Associated With Remission From Alcohol Dependence in an American Indian Community Group

Gilder, David A.; Lau, Philip; Corey, R.N. Linda; Ehlers, Cindy L.

doi:10.1176/appi.ajp.2008.07081308

Cited by 21 publications

(33 citation statements)

References 37 publications

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“…The absence of 12-step research among American Indians is even more perplexing because key predictors of AA affi liation are disproportionately reported among American Indians. Such predictors include severity of alcohol dependence, heavy episodic drinking, and loss of control when drinking (e.g., Gilder et al, 2008).…”

mentioning

confidence: 99%

Longitudinal Study of Urban American Indian 12-Step Attendance, Attrition, and Outcome

Tonigan¹,

Martinez-Papponi²,

Hagler³

et al. 2013

J. Stud. Alcohol Drugs

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ABSTRACT. Objective: Strong opinions have been voiced about the "fi t" between 12-step treatment, community-based 12-step practices, and American Indian beliefs and values. Little is known, however, about the relative benefi t of 12-step programs for urban American Indians, although they are the most widely accessed type of treatment by American Indians. This study investigated rates of 12-step attendance, attrition, and substance use outcomes for American Indians for 9 months relative to non-Hispanic White participants. Method: This study compared urban American Indian (n = 63) and non-Hispanic White (n = 133) 12-step attendance, attrition, and substance use over 9 months. The sample was formed by merging data from two prospective single-group longitudinal studies investigating behavior change in community-based 12-step programs. Participants were interviewed at baseline and at 3-, 6-, and 9-month follow-ups. No intervention was provided. Participants were recruited from Alcoholics Anonymous meetings in the community and as they presented for outpatient substance use disorder treatment.Substance use and patterns of 12-step attendance were measured using the Form 90 calendar-based interview, and the General Alcoholics Anonymous Tools of Recovery was administered to assess the adoption of prescribed 12-step practices and beliefs. Results: Trajectories in 12-step meeting attendance over 9 months did not differ between American Indian and non-Hispanic White participants. However, American Indian participants discontinued 12-step attendance signifi cantly less often than non-Hispanic White participants. Higher rates of 12-step attendance predicted increased alcohol abstinence and decreased drinking intensity for both American Indian and non-Hispanic White participants. Twelve-step attendance was unrelated to later illicit drug use for both American Indian and non-Hispanic White participants. Conclusions: Community-based 12-step program attendance is associated with drinking reductions among urban American Indians. (J. Stud. Alcohol Drugs, 74, 514-520, 2013)

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mentioning

confidence: 99%

Longitudinal Study of Urban American Indian 12-Step Attendance, Attrition, and Outcome

Tonigan¹,

Martinez-Papponi²,

Hagler³

et al. 2013

J. Stud. Alcohol Drugs

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“…В последние годы проблеме достижения ремис-сии при алкогольной зависимости уделяется как в России, так и за рубежом большое внимание [2,4,5,6,7,9,10,11,14,16,17,22,23,26,27,29,31,35,36,37,38,39,41]; исследователи делают акцент на такие аспекты ремиссии, как этапность её формирования и динамика, виды ремиссии, их длительность, причины рецидивирования алкоголизма, прогностические факторы формирования многолетних ремиссий. Существует обилие библиографических источников, где описывается ремиссия при синдроме алкогольной зависимости, однако точных дефиниций понятия «ре-миссия» и критериев её определения недостаточно, имеющиеся формулировки весьма условны [4].…”

Section: Psychology and Psychiatryunclassified

“…Так, по мнению ряда авторов [13,29], у мужчин ремиссии более продолжительные, другие исследователи полагают, что женский пол имеет по-ложительное прогностическое влияние на длитель-ность ремиссии [32,36], или рассматривают пол как независимый фактор [31]. Одни авторы подчёркивают, что продолжительность ремиссий существенно выше у больных в молодом возрасте [38], другие ассоцииру-ют формирование длительных ремиссий со старшим возрастом [13,29,34,36,38,41].…”

Section: Psychology and Psychiatryunclassified

“…Наличие аффективных расстройств, в частности депрессии и тревоги, влияет на устойчивость клини-ческой картины ремиссии и обусловливает высокий риск рецидива [11,31,36,37]. Коморбидная церебраль-ная патология (травматического, гипертонического, вертеброгенного генеза) оказывает модифицирующее влияние на клинико-патодинамические закономер-ности алкоголизма [3].…”

Section: Psychology and Psychiatryunclassified

“…Прогностически благоприятным фактором является высокий образовательный уро-вень [35,37,38,41], стабильные брачные отношения [35,36,37], наличие в семье маленьких детей [35], высокий уровень доходов [41], регулярное посещение религиозных служб [35]. На поддержание ремиссии влияют и такие факторы, как: удовлетворение от рабочей деятельности; занятия физкультурой и спортом; хобби; участие в выполнении круга семей-ных обязанностей во внерабочее время; отсутствие психотравмирующих ситуаций в семье и на работе; полный разрыв общения со злоупотребляющими алкоголь лицами; поддержка родственниками отказа от потребления спиртного [7].…”

Section: Psychology and Psychiatryunclassified

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Factors of Long-Term Remission Formation in Patients With Al-Cohol Dependence

Petrunko¹,

Брюханова²,

Bryukhanova³

2018

Acta Biomedica Scientifica

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Alcohol dependence syndrome is the important modern medico-social issues. In recent years, the problem of achieving remission with alcohol dependence has been given great attention, both in Russia and abroad. The duration, persistence and quality of remission are the indicators of effectiveness of alcohol dependence therapy. The possibility of an objective prediction of the outcome of ongoing therapy, the duration of remissions and the likelihood of relapses of alcohol dependence are urgent needs. Despite a large number of scientific studies, there is no single idea of the factors influencing the formation of remissions in patients with alcoholic dependence syndrome. The article presents the modern view on the terms and stages of the remissions formation in alcohol dependence syndrome, clinical-psychopathologic structure of remissions. Diagnostic assessment of the remissions is examined according to the current classifications of ICD-10 and DSM-V. Biological, personal, social and therapeutic factors of the formation of long-term remissions in patients withВ современной отечественной наркологии к основным показателям эффективности лечения алкогольной зависимости относят длительность, стойкость и качество достигаемых ремиссий. Однако анализ данных литературы свидетельствует о том, что в течение первых шести месяцев при современ-ных методах лечения вероятность срыва ремиссии наблюдается у 60 % больных алкоголизмом [9]. Прогнозирование развития при алкогольной зависи-мости ремиссий, их продолжительности и качества, вероятности рецидивирования позволяет оптими-

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Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol‐related phenotypes in a Native American community sample

Peng

Gizer

Libiger

et al. 2014

American J of Med Genetics Pt B

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Higher rates of alcohol use and other drug-dependence have been observed in some Native American populations relative to other ethnic groups in the U.S. Previous studies have shown that alcohol dehydrogenase (ADH) genes and aldehyde dehydrogenase (ALDH) genes may affect the risk of development of alcohol dependence, and that polymorphisms within these genes may differentially affect risk for the disorder depending on the ethnic group evaluated. We evaluated variations in the ADH and ALDH genes in a large study investigating risk factors for substance use in a Native American population. We assessed ancestry admixture and tested for associations between alcohol-related phenotypes in the genomic regions around the ADH1-7 and ALDH2 and ALDH1A1 genes. Seventy-two (72) ADH variants showed significant evidence of association with a severity level of alcohol drinking-related dependence symptoms phenotype. These significant variants spanned across the entire 7 ADH gene cluster regions. Two significant associations, one in ADH and one in ALDH2, were observed with alcohol dependence diagnosis. Seventeen (17) variants showed significant association with the largest number of alcohol drinks ingested during any 24-hour period. Variants in or near ADH7 were significantly negatively associated with alcohol-related phenotypes, suggesting a potential protective effect of this gene. In addition, our results suggested that a higher degree of Native American ancestry is associated with higher frequencies of potential risk variants and lower frequencies of potential protective variants for alcohol dependence phenotypes.

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Factors Associated With Remission From Alcohol Dependence in an American Indian Community Group

Cited by 21 publications

References 37 publications

Longitudinal Study of Urban American Indian 12-Step Attendance, Attrition, and Outcome

Longitudinal Study of Urban American Indian 12-Step Attendance, Attrition, and Outcome

Factors of Long-Term Remission Formation in Patients With Al-Cohol Dependence

Association and ancestry analysis of sequence variants in ADH and ALDH using alcohol‐related phenotypes in a Native American community sample

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