Conversion of DDT to DDD by BovineRumen Fluid, Lake Water, and Reduced Porphyrins DDD is often detected as a residue in situations where only DDT has been used, and DDD appears to persist for unusually long periods. Studies with C--DDT incubated with bovine rumen fluid, lake water, and aqueous solutions of reduced porphyrins showed partial conversion to C14-DDD. Conversion by bovine rumen fluid may explain certain DDD residues in milk, and conversion by lake water could account for the apparent extraordinary persistence of DDD in Clear Lake, Calif., because DDT may be available as a continuing precursor for DDD in these situations. The study with reduced porphyrins indicates a possible mechanism for this conversion in biological systems.
A-Acetylation of the insecticide Zectran does not greatly alter its toxic effects on spruce budworm, but virtually eliminates toxicity in mice. The fate of acetylated Zectran was investigated by using several radioactive labels. Mice detoxify acetyl
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