Large quantities of presumably nontoxic petroleum oil by-products are introduced into the environment as pesticide dispersal agents and emulsifiers. An increase in viral lethality with a concomitant influence on the liver and central nervous system occurs in young mice previously primed with such chemicals.
The production of interferon by suspensions of human leucocytes has been previously demonstrated(1). The present series of experiments was performed to determine whether (a) mononuclear cells or (b) polymorphonuclear leucocytes or (c) both cell types were responsible for the interferon produced under these conditions.
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