Phytochemicals produced by herbs and medicinal plants have a variety of therapeutic uses. They also help the plant's colour and organoleptic characteristics. Due to their absence of adverse effects, these phytochemicals are used in advanced medical systems to efficiently treat ailments. Because Kigelia Africana contains phytoconstituents, the plant has gained significant scientific attention for its wide range of pharmacological properties. It has been examined and shown to have a number of compounds that treat cancer, psoriasis, dysentery, inflammations, and bacterial infections. The goal of the current investigation was to identify and separate the chemical components found in the fruit extracts of Kigelia africana (Lam.) Benth. Preliminary phytochemical screening performed on n-hexane, chloroform, ethyl acetate, ethanol and aqueous extracts showed the presence of alkaloids, glycosides, phenols, flavonoids etc. The qualitative estimation of the phytoconstituents revealed the presence of total phenols, total flavonoids, total saponins and glycosides as 9.38, 2.64, 3.12 and 6.45 %w/w respectively in the ethanol extract. The ethanol extract was subjected to TLC and coloumn chromatography which resulted in 4 fractions out of which fraction F4 was in significant quantity. It was analyzed using HPTLC that showed the presence of one isolated molecule.
Nature had been serving humanity from ages by providing with the food and resources of our well-being. It was serving with medicines and herbs that are used to heal many disorders. There were numerous lead molecules that had been isolated from natural sources, especially plants. Kigelia africana (Lam.) Benth is a widely distributed plant in Africa. Savage tree or the cucumber plant is the common name of the plant. It belongs to the family Bignoniaceae. The plant is a native plant of Africa which is confined to the south, central and West African regions. Preliminary phytochemical screening was performed for the plant revealed the presence of alkaloids, tannins, saponins, flavonoids, carbohydrates and sapogenetic glycosides. The plant has been reported to contain flavonoids, aldehyde iridioids, coumarins like dihydroisocoumarin, naphthoquinones like pinnatal, isopnnatal, kigelinole and isokigelinole. It had been investigated and proven to possess various chemicals that treat inflammations, cancers, psoriasis, dysentery and bacterial infections.
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