Mode of presentationThe mean age of the 13 children at the time of the initial illness was 9 months (range 7 weeks to 3 years 9 months); however 4 were over 12 months. Five of the children had first-degree relatives with asthma.
Total work of breathing was measured on 55 occasions on 26 babies with acute bronchiolitis using a respiratory jacket to measure tidal volume and a naso-gastric tube to record oesophageal pressure. Work of breathing was increased six-fold on average and on one occasion exceeded forty times the expected. Approximately 40% of the intra-thoracic pressure swing was positive relative to atmospheric. It was not possible to correlate the work of breathing measurements with detailed clinical assessments.
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