In this article,
we designed a fluorometric sensor based on nitrogen-passivated
carbon dots infused with a molecularly imprinted polymer (N-CDs@MIP)
via a reverse microemulsion technique using 3-aminopropyltriethoxysilane
as a functional monomer, tetraethoxysilane as a cross-linker, and
2,4,6-trinitrophenol (TNP) as a template. The synthesized probe was
used for selective and sensitive detection of trace amounts of TNP.
The infusion of N-CDs (QY-21.6 percent) with a molecularly imprinted
polymer can increase the fluorescent sensor sensitivity to detect
TNP. Removal of template molecules leads to the formation of a molecularly
imprinted layer, and N-CDs@MIP fluorescence response was quenched
by TNP. The developed fluorescence probe shows a fine linear range
from 0.5 to 2.5 nM with a detection limit of 0.15 nM. The synthesized
fluorescent probe was used to analyze TNP in regular tap and lake
water samples.
Finger deformities are a major concern among the Indian population, where the increase of risk factors are higher for people suffering from Rheumatoid Arthritis. The deformities hinder the movements in the finger, affecting their day to day activities. Finger splint is a device which is used to support and correct this deformity in order to improve function. Three-dimensional modeling and 3D printing techniques are the standard measures used. The proposed methodology involves 3D modeling which was done using Solidworks 2013, along with standard measurements taken from the patients with deformities due to Rheumatoid Arthritis. The measurements were obtained using a vernier caliper. The 3D printing was done using Fused Deposition Modeling (FDM) and the materials needed for the same are Acrylonitrile Butadiene Styrene (ABS) and flex Polylactic Acid (PLA). The 3D printer used for the same is Flashforge Dreamer 3D printer. The volunteers were fitted with the custom finger splint. The finger splint is light-weight, easy to maintain and clean, with an inventive design based on the finger deformity. It is comfortable and helps support the patients during daily activities. It serves as an easy slip-on. Since it is well-ventilated, swelling of the finger does not occur. Future research will focus on the correction of the deformity, in addition to the biomechanical aspect of finger deformities.
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