Aim. To study the left atrium (LA) remodeling in patients with different body mass, suffering from chronic obstructive lung disease (COLD).
Materials and methods. Seventy two patients with COLD, who were divided into 3 groups, underwent echocardiography: group 1– patients with normal body mass (n = 31), group 2 – patients with excessive weight (n = 21), group 3 – patients with degree I obesity (n = 20).
Results. Among patients with COLD, belonging to group 3, indexed parameters of minimum (15.43 ± 1.62 ml/м2, р = 0.004) and presystolic (20.52 ± 1.88 ml/м², р = 0.03) volumes of LA increased; these patients also demonstrated growth of maximum upper-lower size of LA with elevation of its linear maximum and minimum sizes, when compared with patients of group 1. Patients with different body mass, suffering from COLD, have similar volumes of passive and active depletion and their corresponding fractions. COLD patients with excessive body mass and obesity showed moderate pulmonary hypertension.
Conclusions. Patients with obesity, suffering from COLD, have significantly elevated indexed parameters of presystolic and minimum LA volumes, which can be considered as early markers of impaired function of LA. Increased minimum LA volume can be one of the factors of gas exchange impairment.
Aim. To study the correlation between the body fat mass (BFM) and the structural-functional characteristics of right ventricle (RV) in patients with different body mass, suffering from chronic obstructive pulmonary disease (COPD).
Materials and methods. Echocardiography, ultrasound determination of subcutaneous and premesenterial layer thickness, assessment of leptin level was performed in 72 COPD patients, who were divided into three groups: group 1 – patients with normal body mass (n = 31), group 2 – patients with excess weight (n = 21), group 3 – patients with class I-II obesity (n= 20).
Results. Among COPD patients, body mass index (BMI) growth causes increase in BFM and subcutaneous and premesenterial fat thickness, elevation in blood serum leptin level, but decrease in lean body mass (LBM). The global longitudinal systolic strain of the free wall of RV in COPD patients with obesity (–17.39 ± 3.64, p = 0.002) and elevated body mass (–17.96 ± 5.69, p = 0.006) is reduced.
Conclusions. Among COPD patients with different body mass, the global longitudinal systolic strain of RV free wall aggravates as leptin level and body fat mass grow that can be the reflection of mechanical exposure and epicardial fat pressure on the right ventricle.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.