For transgender, transsexual, genderqueer, and gender nonconforming people, emergent media technologies offer new outlets for self-representation, outlets that often last for only a brief moment. This article examines trans culture on the website Tumblr during the period from March 2011, when the authors began researching the platform, to May 2013, when Yahoo! paid creator David Karp over a billion dollars for the site. Through auto-ethnographic dialogue about the loose social networks within Tumblr to which the authors contributed during this phase, the article explores ephemeral aspects of self-representation at the intersection of postmodern art practice, sexual politics, and queer subjectivities. From at least 2011 to 2013, people collectively oriented in opposition to dominant discourses of gender and sexuality used Tumblr to refashion straight cisgender norms and to create everyday art in a hybrid media space.
Lymphovascular invasion is a hallmark of malignant neoplasms, however the presence of benign epithelium within vessels has been reported in benign processes, albeit infrequently. The proposed mechanism to explain this phenomenon entails mechanical displacement of benign epithelium into the vascular spaces during surgical manipulation or diagnostic interventions. We report a case of numerous benign epithelial vascular emboli in a cholecystectomy specimen. A 29-year-old male presented with acute calculous cholecystitis. Surgery was delayed for several weeks due to COVID-19 infection. Histologic examination of the gallbladder showed subacute cholecystitis, widespread vascular epithelial emboli with associated fibrin deposition and bile embolism supporting an in vivo process. The epithelial emboli were localized in small veins and arterioles with D2–40−/CD31+/CD34+ endothelium. The displaced epithelium showed benign cytologic features, was negative for p53 expression, and had a Ki-67 labelling index like the benign background mucosa, supporting a benign process. There was no evidence of dysplasia or malignancy in the specimen after thorough sampling. Persistent inflammation, mucosal ulceration, transmural mucosal herniation (Rokitansky-Aschoff sinuses), and protracted surgical manipulation secondary to adhesive disease are favored to be the underlying causes of this unusual histologic finding. Although we presume an uneventful outcome, clinical follow up was recommended. COVID-19 infection likely contributed to this phenomenon by causing a delay in the surgical management.
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