The study investigates prevalence of sexual dysfunction (SD), sexual satisfaction and their correlates in the rural female population in China. An anonymous cross-sectional study was carried out in a random sample of 1178 married of age 20-39 years in Dengfeng County, Henan, China. The prevalence of having at least one SD was 43 and 38% of the respondents were satisfied with their sexual life; 64.0% thought that sex was not important to them; and 85.7% believed that they do not have adequate sex-related knowledge. Having SD and high sexual satisfaction were associated with high mental health or vitality quality of life scores and better perceived health status. Other independent predictors of SD included sociodemographic variables, biological variables, life style factors and masturbation. It is concluded that SD was prevalent among the studied women and were associated with mental health. The sexual health among married women needs to be improved in rural China.
The dosage regimen of vancomycin, teicoplanin and daptomycin remains controversial for critically ill patients undergoing continuous renal replacement therapy (CRRT). Monte Carlo simulation was applied to identify the optimal regimens of antimicrobial agents in patients with methicillin-resistant Staphylococcus aureus (MRSA) infections based on the mechanisms of different CRRT modalities on drug clearance. The optimal vancomycin dosage for patients received a CRRT doses ≤ 30 mL/kg/h was 20 mg/kg loading dose followed by 500 mg every 8 h, while 1 g every 12 h was appropriate when 35 mL/kg/h was prescribed. The optimal teicoplanin dosage under a CRRT dose ≤ 25 mL/kg/h was four loading doses of 10 mg/kg every 12 h followed by 10 mg/kg every 48 h, 8 mg/kg every 24 h and 6 mg/kg every 24 h for continuous veno-venous hemofiltration, continuous veno-venous hemodialysis and continuous veno-venous hemodiafiltration, respectively. When the CRRT dose increased to 30–35 mL/kg/h, the teicoplanin dosage should be increased by 30%. The recommended regimen for daptomycin was 6–8 mg/kg every 24 h under a CRRT dose ≤ 25 mL/kg/h, while 8–10 mg/kg every 24 h was optimal under 30–35 mg/kg/h. The CRRT dose has an impact on probability of target attainment and CRRT modality only influences teicoplanin.
Bi-quadratic polynomial approach for global convergent algorithm in high dimensions coefficient inverse problems
Quan-Fang WangMechanical and Automation Engineering, Chinese University of Hong Kong, Shatin, N.T., Hong Kong E-mail: quanfangwang@hotmail.com Abstract. Sequential minimization algorithm in convexification approach established a stable approximate solution via minimizing a finite sequence of strictly convex objective function. Its application to 1D/2D dimension cases is reported in a great deal literatures. An interesting question should be asked is how about the development of the convex approach to high dimension case. That is to say, whether the approach could be applied to realistic three dimensions issue by a routing way. It becomes a much more challenging topic in present research. In this work, a newly modified global convergent algorithm for recovering the profile of coefficient inverse problems will be constructed by using so-called bi-quadratic polynomial (BQP) in 2D/3D cases. Hope the developed paradigm would be applied in a broad class application.
Electric-pulse-induced resistance (EPIR) switching behaviour was observed in bulk La0.7Ca0.3MnO3 polycrystalline. Temperature dependences of resistance and magnetic moment at different resistance states were studied. The metal–insulator phase transition temperature changed with the resistance states, which suggested that the EPIR phenomenon is related to the modulating bulk properties of perovskite manganites. The Curie temperature derived from the magnetic moment measurement did not change with the resistance states, which implied that there was no ferromagnetic–metal and antiferromagnetic–insulator transition occurring in perovskite manganite global materials. These results provided a new evidence for a filamentary mechanism in the EPIR effect.
The asymmetric fatigue behaviour of electric-pulse-induced resistance switching, that is, only switching from a low to a high resistance state, exhibits obvious fatigue behaviour and has been investigated in Ag–La0.7Ca0.3MnO3–Pt heterostructures. This asymmetric fatigue is strongly dependent on the applied electric-pulse voltage and can be refreshed by applying a voltage sweep in vacuum condition (<100 Pa). The fatigue and its refreshment are related to the increase and decrease in threshold voltage in the resistance switching, respectively. The results indicate that fatigue endurance in resistance switching of Ag–La0.7 Ca0.3MnO3–Pt heterostructures can be improved through the operation of environmental oxygen pressure.
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