Rapid development of aquaculture industry requires many effective disinfectants to deal with various diseases. Meanwhile, abuse of disinfectants caused different effects on the environment (Anjur et al., 2021;Guardiola et al., 2012;Li et al., 2011). Povidone iodine is formed by the combination of iodine elemental and polymer carrier with bactericidal effects (Xu & Guan, 2020). Over the past 60 years, PVP-I has been used to prevent the spread of diseases (Walter Sneader, 2005).It not only has a broad antibacterial and antifungal activity, but also can kill a range of virus, including the related SARS-CoV and MERS-
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