HC is frequently present in patients with OP regardless of the underlying bone turnover status. This may suggest the presence of a bone-derived renal calcium regulating factor(s). Further studies are needed to understand the exact mechanism and the potential consequences of HC in OP patients. .
Wind energy is crucial renewable and sustainable resource, which plays a major role in the energy mix in many countries around the world. Accurately forecasting the wind energy is not only important but also challenging in order to schedule the wind power generation and to ensure the security of wind-power integration. In this paper, four kinds of hybrid models based on cyclic exponential adjustment, adaptive coefficient methods and the cuckoo search algorithm are proposed to forecast the wind speed on large-scale wind farms in China. To verify the developed hybrid models’ effectiveness, wind-speed data from four sites of Xinjiang Uygur Autonomous Region located in northwest China are collected and analyzed. Multiple criteria are used to quantitatively evaluate the forecasting results. Simulation results indicate that (1) the proposed four hybrid models achieve desirable forecasting accuracy and outperform traditional back-propagating neural network, autoregressive integrated moving average as well as single adaptive coefficient methods, and (2) the parameters of hybrid models optimized by artificial intelligence contribute to higher forecasting accuracy compared with predetermined parameters.
Compared with conventional vehicles, autonomous vehicles (AVs) are featured by increased energy efficiency and road safety, yet hardly meet with much success without enough human trust. Designing appropriate interactions between AV and human, such as communication with pedestrians, could help enhance trust and public acceptance. In this work, we examine design characteristics of AV interface, including communication style, explicit display of vehicle speed, and adaptive strategy, and study their effects on pedestrians' trust behaviors. It is found that any communication style could improve pedestrians' trust in AV and decision alignment with AV expectations. Among advisory, commanding, and informative styles, the first two are more effective. Adding speed info on top of explicit message communication does not change the relative effectiveness of individual styles, even though the display of speed only has a significant lift on both measures. In addition, applying an adaptive communication strategy when yielding would significantly improve pedestrians' trust and decision alignment. This study demonstrates the influence of design characteristics on the formation of trust relationships between pedestrians and autonomous vehicles, and paves the ways for developing more advanced AV communication mechanisms.
Pediatric obesity is a significant public health problem, the negative outcomes of which will challenge individual well-being and societal resources for decades to come. The objective of this study was to determine the effects of dietary counseling on weight management and metabolic abnormalities in children with obesity. One hundred and sixty-five patients aged 2–18 years old were studied over a two and a half year period. Data collected included demographic information, anthropometric assessment, laboratory measurements, and self-reported eating behaviors. Dietary counseling was provided at each visit. The data was analyzed from the first and last visits and the subjects were retrospectively divided into responders and non-responders based on a decrease in their BMI. After receiving dietary guidance, BMI decreased in 44% of the children, and these participants were classified as responders (BMI-R; n = 72). However, BMI did not improve in 56% of the participants, and these were classified as non-responders (BMI-NR; n = 93). At the initial visit, anthropometric measurements and dietary habits were similar between the groups. At the time of the last visit, mean change in BMI was −1.47 (SD 1.31) for BMI-R and +2.40 (SD 9.79) for BMI-NR. Analysis of food intake revealed that BMI-R significantly improved their dietary habits (p = 0.002) by reducing the intake of sugar-sweetened beverages (p = 0.019), processed foods (p = 0.002), sweets (p < 0.001), and unhealthy snacks (p = 0.009), as compared with BMI-NR. There was no change in the intake of second helpings, portion sizes, skipping meals, frequency of meals eaten at school, condiment use, intake of fruits and vegetables and consumption of whole grains between the groups. BMI-R also achieved an improvement in fasted glucose (p = 0.021), triglycerides (p < 0.001), and total cholesterol (p = 0.023), as compared to BMI-NR. In conclusion, children with obesity who were able to decrease their BMI implemented a significant reduction in consumption of foods with high sugar content. Focusing on reducing sugar intake may yield the biggest impact in terms of weight management and the improvement of metabolic abnormalities.
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