Two new sulfated triterpene glycosides, philinopsides A (1) and B (2), were isolated from the sea cucumber Pentacta quadrangularis. Their structures were established by extensive spectral analysis (2D‐NMR and MS) and chemical evidence. Philinopside A (1) and B (2) showed significant cytotoxicity (ED50 0.75–3.50 μg/ml) against ten tumor cell lines. Compound 1 also significantly inhibited the proliferation, migration, and tube formation of human microvascular endothelial cells.

No abstract

The structures of two flavanonol glycosides isolated from Smilax glabra, named smitilbin and neosmitilbin, have been revised to isoastilbin and neoastilbin, respectively. The revised structures were determined based on intensive studies of chemical interconversion, NMR spectroscopy, and X-ray crystallographic analysis. The latest NMR data were also summarized.

ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.