Three patients with exogenous lipoid pneumonia are presented. All of them had laryngectomy because of the cancer of larynx. In a period of time ranging from a few months up to a few years after the operation they started to have dyspnoea, cough, sometimes hemoptysis and slightly elevated temperature. The chest X-ray revealed massive opacities in the lower zones of both lungs suggesting lung cancer or metastases of the laryngeal cancer. HRCT showed ground glass lesions. Histological examination of the lungs detected accumulation of multiple macrophages with vacuolated foamy cytoplasms in the alveoli. Neoplastic disease was excluded. Additional data from the patients history revealed that all of them were inhaling or administering mineral oil-containing products through the tracheostomy. Exogenous lipoid pneumonia was diagnosed. Patients were asked to stop inhalations with the mineral oil.
Obstructive sleep apnea (OSA) is one of the most often sleep disturbance. Not treated patients have 2-3 times more risk for death because of the cardiovascular diseases. Leptin and homocysteine are the risk factors for cardiovascular diseases. Treatment by nCPAP has positive influence for health care and reduction of hypertension in this group. The aim of this study was to evaluate an effect of 3 weeks nCPAP therapy on a serum leptin and homocysteine concentrations in patients with OSA. Material and methods: The study group consisted of 48 male patients in the age x=51,2?7,5 years old, OSA was diagnosed by polisomnographic study The leptin concentration was evaluated by RIA methods (HUMAN LEPTIN RIA KIT), the homocysteine concentration was evaluated byAxis Homocysteine EIA test. Patients were treated by nCPAP during 3 weeks. Only 29 patients were effectively treated for this time. The compliance was: 5.07 ±1.81 h Results: In the group of 29 patients the serum leptin and homocysteine concentration before and after treatment were 11,05±5,59 ng/mL vs 11,07±7,16 ng/mL i 10,98±2,79 μmol/L vs 10,34±2,99 μmol/L. In the all study group the statistical important correlation between leptin and AHI, mean and minimal saturation overnight, fibrinogene concentration, BMI, WHR, waist circumference, heart rate and between homocysteine and heart rate were observed. Conclusions: 3 weeks therapy does not have any effect on leptin and homocysteine concentrations in the studied group of patients with OSA. Serum leptin concentration correlates with AHI, TMB90, as well as with mean and minimal saturation during a sleep. This indicates a potentially higher risk of cardiovascular diseases in the studied group.
Hipoksemiczna niewydolność oddechowa u chorego z cechami choroby śródmiąższowej jest rzadko kojarzona z przyczyną pozapłucną. U chorych na marskość wątroby hipoksemia może być manifestacją zespołu wątrobowo-płucnego, jednak zmiany w badaniu radiologicznym klatki piersiowej stwierdzane w przebiegu tego zespołu mają zwykle charakter naczyniowy, a więc nie są zaliczane do typowych chorób śródmiąższowych. W pracy przedstawiono przypadek chorego z ciężką hipoksemiczną niewydolnością oddechową, u którego rozpoznano jednoczasowo zespół wątrobowo-płucny i chorobę śródmiąższową płuc o nieustalonej etiologii. W dyskusji omówiono mechanizmy hipoksemii w przebiegu niewydolności wątroby oraz spektrum chorób dotyczących płuc i wątroby przebiegających z hipoksemią.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.