Tłuszczowe zapalenie płuc u chorych po laryngektomii

Abstract

Three patients with exogenous lipoid pneumonia are presented. All of them had laryngectomy because of the cancer of larynx. In a period of time ranging from a few months up to a few years after the operation they started to have dyspnoea, cough, sometimes hemoptysis and slightly elevated temperature. The chest X-ray revealed massive opacities in the lower zones of both lungs suggesting lung cancer or metastases of the laryngeal cancer. HRCT showed ground glass lesions. Histological examination of the lungs detected accumulation of multiple macrophages with vacuolated foamy cytoplasms in the alveoli. Neoplastic disease was excluded. Additional data from the patients history revealed that all of them were inhaling or administering mineral oil-containing products through the tracheostomy. Exogenous lipoid pneumonia was diagnosed. Patients were asked to stop inhalations with the mineral oil.

Exogenous Lipoid Pneumonia Induced by Nasal Instillation of Paraffin Oil

“…This form of disease concerns adults with chronic obstipation treated with oil-based laxatives, chronic rhinopharyngeal diseases treated with nasal drops, or due to aspira-tion-related syndromes in patients with impaired mental status or impaired swallowing mechanism [5]. Rare cases of exogenous lipoid pneumonia are mentioned in the literature after aspiration during 'fire-eating' or in patients after laryngectomy due to administration of mineral-oil containing products through the tracheostomy [3,4,6]. In our case report, we present an example of exogenous form of lipoid pneumonia, caused by chronic nasal drop use, in a patient with deviated nasal septum.…”

“…Lipoid pneumonia is an uncommon condition, initially described in 1925 by Laughlen in autopsy series of three children and one adult [1,2]. Its clinical incidence is difficult to precise, however, one American autopsy study has reported the frequency of 1.0-2.5% [1,3,4]. Exogenous lipoid pneumonia may occur in subjects of any age, however, it is more likely to affect the elderly, particularly those who have a history of chronic laxatives or nasal drop use.…”

Toxic Lung Injury in a Patient Addicted to “Legal Highs” – Case Study

“…Lipid pneumonia is a rare pulmonary disease. It results from damage to the lung parenchyma by lipid molecules originating from the serum (endogenous form) or entering the lung by aspiration or inhalation (exogenous form) [ 13 – 16 ].…”

Powikłania ogólne operacji nowotworów złośliwych głowy i szyi

“…[225]. Jest ono spowodowane przez aspirację lub inhalację oleju mineralnego, rzadziej oleju roślinnego bądź tłuszczu zwierzęcego.…”

“…Do jego wystąpienia predysponowane się starsze osoby, stosujące w sposób przewlekły parafinę jako środek przeczyszczający [198,225].…”