Intervenção nutricional educativa como ferramenta eficaz para mudança de hábitos alimentares e peso corporal entre praticantes de atividade física Educational nutritional intervention as an effective tool for changing eating habits and body weight among those who practice physical activities
The present study reports the effects of a high-fat (HF) diet of over 8 weeks on the Fe status of growing rats. Tissue Fe levels were analysed by atomic absorption spectrophotometry, and whole-body adiposity was measured by dual-energy X-ray absorptiometry. Histopathology and morphometry of adipose tissue were performed. Liver homogenates were used for measuring ferroportin-1 protein levels by immunoblotting, and transcript levels were used for Fe genes measured by real-time PCR. Tissue Fe pools were fit to a compartmental biokinetic model in which Fe was assessed using fourteen compartments and twenty-seven transfer constants (kj,i from tissue ‘i’ to tissue ‘j’) adapted from the International Commission on Radiological Protection (ICRP) 69. Ten kj,i were calculated from the experimental data using non-linear regression, and seventeen were estimated by allometry according to the formula ${k_{i,j}} = a \times {M^b}$. Validation of the model was carried out by comparing predicted and analysed Fe pool sizes in erythrocytes, the liver and the spleen. Body adiposity was negatively associated with serum Fe levels and positively associated with liver Fe stores. An inferred increase in Fe transfer from bone marrow to the liver paralleled higher hepatic Fe concentrations and ferritin heavy-chain mRNA levels in the HF diet-fed animals, suggesting that liver Fe accumulation occurred at least in part due to a favoured liver erythrocyte uptake. If this feeding condition was to be prolonged, impaired Fe decompartmentalisation may occur, ultimately resulting in dysmetabolic Fe overload.
A Deus, inteligência suprema do Universo, Pai de todas as Ciências por me abençoar tanto .
Aos meus pais EdivanioTeixeira e Aparecida Teixeira , e irmãos João Gabriel e Edivanio Júnior, minha família , por serem minha base e porto-seguro, por acreditarem em mim e estarem sempre ao meu lado, por compreenderem minha ausência física e por serem tão presentes em todos os momentos .. . Meu amor e meus agradecimentos! Ao meu companheiro , por me incentivar tanto, por compreender minhas necessidades, por acreditar tanto em mim , por ser um exemplo de dedicação e persistência .. . Erick Sacramento : te amo e agradeço por tudo! À professora doutora Célia Colli , minha orientadora, obrigada pelo acolhimento, pela confiança , pelos ensinamentos ... Obrigada, professora , por cada oportunidade! À professora doutora Raquel Simões Mendes-Netto por ser um exemplo e me incentivar a trilhar este caminho . Às amigas Diva Vieira e Bruna Reis por todos os desafios que enfrentamos juntas no início desta jornada .
This study evaluated the contribution of diet composition in physically active women to test the hypothesis that energy, lipids, carbohydrates and fiber are the nutrients that directly affect obesity in this population. We used a cross-sectional analysis of 165 adult women who practice at least 150 minutes of moderate physical activity per week. The outcome variables were body mass index (BMI) and waist circumference (WC). Individuals were classified into groups according to BMI as either obese or non-obese (BMI ≥ 30 kg/m² or < 30 kg/m², respectively), and by WC as either with risk or without risk (WC ≥ 88 cm or <88 cm, respectively). Dietary intake was assessed by a 24-hour dietary recall. A multiple means (ANOVA) was used to compare the mean consumption of the groups. In this study, 69.1% of women were overweight or obese. Obese women consumed significantly more energy and cholesterol and less carbohydrate (p <0.05) and tended to have a lower intake of fiber (p <0.10) than the nonobese women. Moreover, women with higher WC consume significantly more energy (p <0.05) and tend to have a lower consumption of carbohydrates and fiber (p <0.10) than women with minor WC. The results showed that, despite being physically active, the women studied had an average BMI indicative of obesity, showing that dietary patterns are highly correlated with this condition. We found that low consumption of carbohydrates and fiber and high consumption of energy and cholesterol contributed significantly to obesity among women.
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