Medicinal chemistry has been benefited by combinatorial chemistry and high throughput parallel synthesis. The use of sonochemistry under controlled conditions has been proved beneficial for medicinal chemistry and drug discovery process since it dramatically reduces reaction times, from days or hours to minutes. In addition, sonochemistry synthesis provides higher yields, lower cost, easy workups and greater purity as compared to lower yields, tedious workups, longer reaction times, lesser purity and termination of many by-products in the conventional thermal methods.
Relevance of Sonochemistry or Ultrasound (US) as a Proficient Means for the Synthesis of Fused Heterocycles-[52 refs.]. -(PATIL, R.; BHOIR, P.; DESHPANDE, P.; WATTAMWAR, T.; SHIRUDE, M.; CHASKAR, P.; Ultrason. Sonochem. 20 (2013) 6, 1327-1336, http://dx.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.