On the basis of analysis of 17,151 records on zebrafish identified from Zebrafish Information Network: the zebrafish model organism database and Web of Science, the research performance on this model organism has been evaluated. The earliest research work on zebrafish as reflected in the databases goes back to 1951. After a rather slow growth till the 1980s, research on zebrafish gained momentum in the 1990s. Analysis shows a rapid and consistent increase in the publication output with 226 publications in the year 1996, to 1929 publications in the year 2012. The prominent areas of zebrafish research, journals, and leading authors as reflected from the research output have been identified. USA is the most productive country with 8196 articles. The most frequently used keywords were also determined to gain insights about the research trends and some of the commonly used keywords other than zebrafish and Danio rerio are development, retina, and gene expression.
The excitement about nutrigenomics comes from a growing awareness of the potential for modifications of food or diet to support health and reduce the risk of diet-related diseases. It is an emerging field that tends to unfold the role of nutrition on gene expression which brings together the science of bioinformatics, nutrition, molecular biology, genomics, epidemiology, and molecular medicine. The present review focuses on nutrigenomics research and to find out India's status with respect to other countries. It covers the general overview of nutrigenomics, its associated diseases, and the role of SNP in gene alteration, diet supplementation and public awareness. It is understood that with the increasing changes in the food habits and life styles, people are becoming more prone to diet related disorders. Therefore there is an urgent need to boost more research in this field to help people in understanding the relationship between diet and health, and to ensure that everyone benefits from the genomic revolution.
The basic concept behind the emergence of nutraceuticals is an ancient one i.e. disease prevention with food rather than medicine. But this concept has given rise to different terminologies across the globe and different countries have their own set of guidelines and agencies to regulate them and related activities. This review article gives a snapshot of those terminologies, agencies and the regulatory guidelines. The study highlights the key features of the regulatory process with the aim to achieve global harmonization. Special focus has been given to the issues that exist in the new Food Safety and Standards (Health Supplements, Nutraceuticals, Food for Special Dietary Use, Food for Special Medical Purpose, Functional Food and Novel Food) Regulations, 2016, laid down by FSSAI. The article concludes by highlighting existing issues and possible suggestions that will effectively help in dealing with nutraceuticals without compromising consumers" safety.
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