Condyloma acuminata (CA) known as anogenital wart is the most frequent sexually transmitted infection worldwide. This highly infectious disease is caused by the human papilloma virus, whose its high reccurence rates contribute to direct medical costs, productivity loss and increased psychosocial impact. Thus, the prevention of this viral disease is more important than focusing on its treatment. This cross sectional retrospective study assesed the gender differences in sociodemographic characteristics and sexual risk factors of CA patients. There were 94 newly diagnosed CA patients, 47 males (50%) and 47 females (50%) during the period of January 2013- December 2017. The demographic data were taken from medical record and the additional data about the risk factors were from the questionnaires. Chi-square test was performed to compare between genders and p < 0.05 was considered statistically significant. There was significant difference between genders on all sociodemographic characteristics (age, occupation, education, marrital status) and risk factors (HIV/AIDS infection, condom using, age at the first sexual intercourse, number of lifetime sexual partner, type of intercourse) among CA patients. Our study revealed that male CA patients were mostly single, employed and multipartner, while CA female patients were mostly married, housewives and singlepartners.

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Introduction Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute severe cutaneous adverse reactions commonly caused by medication. Precise evaluation of disease severity in initial setting must be obtained to start appropriate treatment. Neutrophil and lymphocyte ratio (NLR) plays a role in displaying inflammatory reaction while eosinophils count (EC) influences immunological dysregulation including the proliferation of cytotoxic cells in early onset of SJS/TEN. Objective To evaluate whether NLR and EC serve as prognostic markers of disease severity in patients with SJS/TEN using SCORTEN. Methods A single center study with retrospective study included SJS/TEN patients at Dr. Moewardi General Hospital Surakarta in January 1st 2018–December 31st 2020. The required laboratory data was assessed at the beginning of the patient’s admission through medical records. The significance analysis were performed using one-way ANOVA and Spearman while the receiver-operator curve were used to evaluate the prognostic value of variables for severity in SJS/TEN patients. Results The total sample in this study was 24 patients with majority female (58%) and range from 25 to >50 years (54%). The results demonstrated of significant difference and positively correlated between NLR and EC with severity of SJS/TEN (p<0.01; r>0.05). The specificity and sensitivity of 51%;61% and 70%;60%, respectively. Conclusion NLR and EC can be used as prognosticators of severity in SJS/TEN while further research on other inflammatory markers with increased number of samples and study centers are needed to provide more actual data.

Background: Acne scar is the most common complication in acne that occurs in about 49% of acne individuals. Fractional resurfacing lasers such as CO2 laser and erbium-doped yttrium aluminum garnet (Er: YAG) have been widely used for acne scar treatment and give satisfying results have complications such as pain, hyperpigmentation, infection, prolonged erythema, and scarring. Fractional erbium: yttrium scandium gallium garnet (Er: YSGG) laser solves previous laser techniques' disadvantages. It has an ideal wavelength of 2790 nm, which balances the epidermis layer's vaporization and thermal damage in the dermis's superficial layer. Platelet Rich Plasma (PRP) is an autologous concentration of human platelets in a small plasma volume that secreted various growth factors that can speed up the scar healing process.Case report: A-24 years old male student came with a chief complaint of acne scars on his face four years before the examination. The patient's condition is classified as moderate-severe acne scarring based on Goodman and Baron's criteria (qualitative global acne scarring system). Acne scars treatment plan was single fractional erbium: YSGG laser for the left side of the face and combined fractional Er: YSGG laser with topical autologous PRP on the right side. This procedure was performed in 2 sessions with an interval of 4 weeks, the final evaluation at 12 weeks after the first procedure. Clinical improvement of acne scars was assessed using qualitative and quantitative scales based on Goodman and Baron's, patient and observer scar assessment scale (POSAS), quartile grading scale, and patient satisfaction level.Conclusion: In the final evaluation, there was an improvement on the entire grading scale on the right side of the face (Er: YSGG laser + PRP) and the face's left side (Er: YSGG laser only). Post-treatment erythema was found on both sides of the patient's face but disappeared within three days on the face's right side and five days on the face's left side.

Basal Cell Carcinoma (BCC) incidence is 75% of all skin cancers. BCC rarely causing mortality, but morbidity is high. Clinical diagnostic is the early detection of BCC suspicion, therefore, we required speci� c criteria that help to establish the clinical diagnosis. The objective of this study was to know the clinical sign as a predictor of basal cell carcinoma. Ten patients with skin tumors who came to dermatovenereological department of Dr. Moewardi hospital were included in this study. Clinical diagnosis using clinical criteria from keratinocyte carcinoma in A Cancer Journal For Clinicians in 2011 (Teleangiectasion, raise border, erythematous with bleeding, pigmentation, translucent appearance, and scarlike appearance) was used as reference of clinical diagnostic criteria. Histopathological examination was performed as a gold standard. All 10 subjects had histopathological � nding consistent to BCC. The clinical examination like pigmentation were found in all subjects while teleangiectasia, raise border, erythema with bleeding were found on 9 subject. Translucent appearance was found on 6 subjects. While scarlike appearance was absent in all subjects. The criteria from keratinocyte carcinoma in A Cancer Journal For Clinicians in 2011 can be used to diagnosed BCC clinically

Acne vulgaris (AV) is the most common and multifactorial skin disease in adolescents affecting the pilosebaceous unit that involves hormonal imbalance, increased sebum production, and bacterial colonization, which causes both physical and psychological disorders. Cutibacterium acnes is considered one of the key contributing factors even though many Cutibacterium acnes colonies are on healthy skin. Cutibacterium acnes induces lipogenesis and production of sebum. Through its production of porphyrins, it may act as a catalytic agent in squalene oxidation that is comedogenic, thus aggravating comedogenesis. We review the dual role of Cutibacterium acnes to provide an understanding of the pathophysiology of acne vulgaris.

Background:The incidence of Sexually Transmitted Disease (STD) infection in gay, homosexual, and men who have sex with men (MSM) is greater than that reported in women and men who have sex with women only (MSW). As some of the affected are left untreated, elevated burden of STD is of concern. The high incidence of STD infection among MSM may be related to various individual behaviors and characteristics. This study aimed to determine the profile and risk factors of STD infection among MSM and transgender in Surakarta. Subjects and Method: This was a cross-sectional study conducted at Community Health Centers and Dr. Moewardi Hospital in Surakarta, Central Java, from March to July 2017. A sample of 190 study subjects was selected for this study. The dependent variable was HIV and STD infection. The independent variables were sexual orientation (MSM and transgender), marital status, education, meeting location of couples, and number of sexual partners. The data were collected by a set of questionnaire. Data on HIV and STD infection was obtained by various blood examination, including: syphilis, gonorrhea, non-specific urethritis, and non-specific proctitis, and acetowhite lesion examinations. The bivariate analysis was performed by chi square. Results: As many as 65 (34.2%) of the study subjects had HIV reactive. 67 (35.3%) had STD, consisting of 39 (20.5%) syphilis. 26 (13.7%) had ano-genital warts (23 anal warts and 3 penile warts). 1 (0.5%) had gonorrhea. 14 (7.4%) had non-specific proctitis. 32 (16.8%) aged <25 years, 158 (83.1%) aged over 25 years. 143 (75.3%) were single, and 109 (57.4%) had bisexual orientation. 35 (18.4%) had ≥ high school education and 145 (88.6%) had < high school. The risk of HIV and STD infection was associated with sexual orientation (MSM and transgender), education, marital status, meeting location of couples, and number of sexual partners. Conclusion:The risk of HIV and STD infections is associated with sexual orientation (MSM and transgender), marital status, education, meeting location of couples, and number of sexual partners.