Background: Multi-drug resistant tuberculosis has emerged as a significant problem with the resurfacing of tuberculosis and thus the need to use the second line drugs with the resultant increased incidence of adverse effects. We discuss the effect of second line aminoglycoside antitubercular drugs on the hearing status of MDR-TB patients.
Dacryocystorhinostomy is performed in patients with naso-lacrimal duct obstruction to bypass the site of obstruction so as to relieve the patient of the irritating and socially embarrassing symptoms of epiphora. We discuss the various epidemiological aspects especially the vast difference by which the females out-number the males in patients undergoing DCR and the likely explanations for this difference in our study on 74 patients which underwent DCR in our institute.
Background: We report a case of vascular malformation arising from internal jugular vein presenting as mass at root of neck with no clinical stigmata which to the best of our knowledge is the first reported case of an intrinsic vascular malformation arising from the internal jugular vein. Magnetic resonance imaging features of this new entity have been described.
Aim Primary ablative surgery followed by post-op radiotherapy (S-RT) remains the mainstay of treatment for stage IIIstage IV oral carcinoma. A retrospective analysis of survival rates of advanced-stage OSCC patients treated with multimodal therapies (S-RT or combined chemoradiation) was performed to analyse the outcome for patient survival and whether addition of adjuvant chemotherapy (S-CRT) improves survival. Materials and Methods Demographic, pathological, treatment and follow-up data of 128 patients were included in the study. Sixty-nine patients received S-RT, while 55 patients were opted for S-CRT. Overall survival, diseasespecific survival and disease-free survival were estimated with Kaplan-Meier analysis and compared between groups with Cox regression analysis. Results Survival was significantly influenced by the type of modality and regional spread of disease. S-CRT group had improved overall, disease-specific, disease-free and metastasis-free survival compared to S-RT group. A survival advantage of 10% was achieved in S-CRT group compared to S-RT group even in patients with extracapsular spread and perineural invasion. Conclusion Addition of adjuvant chemotherapy to S-RT improves survival outcomes in advanced OSCC, especially in patients with regional spread of disease.
We report a case of monostotic fibrous dysplasia of temporal bone in a 15-year-old male which presented with mass in the temporomastoid region. There was no associated complaint and patient came only for cosmetic correction of the asymmetry of skull. Conductive hearing loss was an incidental finding on audiogram. Computed tomography showed increased bone thickness with ground glass appearance. Shaded surface display of the skull was used in assessing the external bony deformity. Patient was operated for contouring of the bone and canalplasty which improved the cosmetic appearance as well as corrected the hearing loss thereby avoiding an extensive surgery. Patient is under regular follow-up with good cosmetic and functional results. This case highlights the importance of conservative surgery and regular follow-up in selective cases of temporal bone fibrous dysplasia along with use of shaded surface display for planning the correction of external deformity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.