BACKGROUND/AIMS: Birth asphyxia occurs when a baby does not receive enough oxygen before, during or after birth . It is an insult to the fetus or newborn due to lack of oxygen (hypoxia) and /or a lack of perfusion (ischemia) to various organs . Fetus totally depends for its oxygen supply and other nutrients on the blood supplied through placenta. In any case, if blood supplied through placenta is hampered, it leads to asphyxial injury. We performed this study to determine the incidence of liver failure in birth asphyxia and to correlate the severity of hepatic disorder with asphyxia by estimating serum AST and ALT. MATERIAL AND METHODS: The study included 70 asphyxiated neonates and 50 healthy neonates as controls. Serum AST and ALT were estimated by IFCC method for Aspartate aminotransferase and IFCC method for Alanine aminotransferase respectively. RESULT: Serum AST and ALT were found significantly higher in asphyxiated babies compared to control groups (p<0.001). The mean AST and ALT of asphyxiated babies were 80.3±47.4 U/L and 88.8±43.5 U/L, respectively and those of normal babies were 20.5±8.5 U/L and 27.5±8.5 U/L respectively. The rise of AST and ALT also showed a significant positive correlation with the severity of asphyxia. Hence it can be concluded from present study that estimation of hepatic enzymes can be used as markers to diagnose the incidence of perinatal asphyxia and also to assess its severity.
BACKGROUND/AIMS: Osteoarthritis is an inflammatory & degenerative disorder of joints. The exact pro-oxidant & antioxidant status is not clear in osteoarthritis. Our aims were to estimate levels of the lipid peroxidation (in terms of MDA) & enzymatic antioxidant (in terms of superoxide dismutase) in serum of osteoarthritis patients & compare them with the levels in normal healthy controls. MATERIAL & METHODS: A study was performed at the department of biochemistry at Pd. Dr. D. Y. Patil medical college, Pimpri, Pune-18(M.S.) In 30 patients of osteoarthritis serum levels of enzymatic antioxidant Marker (SOD) & lipid peroxidation status (MDA) were estimated by spectrophotometry. Thirty healthy controls were also included in the study & serum levels of same parameters were also measured. STATISTICAL ANALYSIS: It was performed by using the student unpaired t test. RESULT: A serum level of enzymatic antioxidant marker (SOD) was increased in the patients than in the controls. The serum lipid peroxidation (MDA) level was increased in the patients than in the controls.
BACKGROUNDThere are various measures used in formative assessment such as Essay Questions (EQ), Short-Answer Questions (SAQ), MultipleChoice Questions (MCQ) and Long Answer Questions (LAQ).The aim of the present study was to find out the effectiveness of SAQ and LAQ in assessing cognitive domain among First MBBS students.
BACKGROUND/AIMS: Birth asphyxia occurs when a baby does not receive enough oxygen before, during or after birth. It is an insult to the fetus or newborn due to lack of oxygen (hypoxia) and /or a lack of perfusion (ischemia) to various organs. Fetus totally depends for its oxygen supply and other nutrients on the blood supplied through placenta. In any case, if blood supplied through placenta is hampered, it leads to asphyxial injury. We performed this study to determine the incidence of renal failure in birth asphyxia by estimating serum creatinine, blood urea and blood urea nitrogen / creatinine ratio on I & III day of life. MATERIAL AND METHODS: The study included 50 asphyxiated neonates and 25 healthy neonates as controls. Blood urea and serum creatinine were estimated by Vitros 950 dry chemistry autoanalyzer. RESULT: Blood urea and serum creatinine were significantly higher in asphyxiated babies compared to control groups (p<0.001). Blood Urea nitrogen / Creatinine ratio was significantly higher in asphyxiated babies compared to control groups (p<0.001) on day 3 but insignificant on day 1. We conclude that renal failure is a significant problem in asphyxiated neonates.
Background: Comparative study of serum calcium, magnesium, uric acid and glucose in preeclampsia and normal pregnant women of malwa region of Madhya pradesh Methods: For the Study, a total of 100 women ranging in age from 18-35 years were recruited. They were divided in two groups. 50 were pre-eclamptic women with gestational age of ?20 weeks (Case group) and rest 50 were normal pregnant women of same gestational age (Control group).The levels of magnesium, calcium, glucose, and uric acid in the blood were measured. Result: Serum calcium and magnesium levels were significantly lower (p<0.001) in the pre-eclamptic group, whereas serum uric acid levels were significantly higher (p0<001) in preeclamptic group. The level of serum glucose was raised in preeclampsia. Conclusion: serum levels of calcium, magnesium, uric acid and glucose are altered in pre-eclampsia, implying that these factors may play a role in the aetiology and severity of pre-eclampsia.so assessing the serum level of this parameters will aid in the early detection of pre-eclampsia. Keywords: Calcium, Magnesium, Uric acid, Glucose, Pre-eclampsia, Pregnancy
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.