In recent years, Dakin oxidation evolved primarily around the conversion of ortho and para-hydroxy benzaldehydes and acetophenones to dihydric phenols, which is found in nature and complex organic materials. In...

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In organic synthesis, decarboxylation and C-H bond functionalization are two major processes. Direct C-H bond functionalization of cyclic ethers through decarboxylation by using electronically diverse cinnamic acid derivatives in presence...

The C-2 selective direct functionalization of N-methylindole derivatives with aryl iodides catalyzed by Pd supported on carbon is developed. This methodology exclusively results in C-2 arylated indoles in the absence of any ligand or directing group. The catalyst is easily recoverable from the reaction mixture and can be reused up to four cycles without any significant loss of its catalytic efficiency. Without using any additive, the current protocol is applicable for a wide range of substrates.