This study aimed to evaluate the wound healing property of Rubia cordifolia Linn in wistar albino rats in burn wound model where rats' dorsum were placed on wooden template and metallic screen. Both the template and screen were immersed in hot water bath for sixty seconds maintained at a temperature of 100 0 C. Animals were divided into three groups comprising of six animals each. Control group received the vehicle, standard group received silver sulfadiazine and test group were treated with paste of Rubia cordifolia as a topical application respectively. The topical application of test drug has shown significant wound contraction (**P<0.01) in comparison to normal control group. This was supported by the histopathological findings with good epithelialisation of cells when compared to normal control group.
C. serratum and S. xanthocarpum plants are used as folk remedies for inflammations, arthritis, cough, asthma and bronchitis. The present investigation aimed to evaluate the comparative anti-inflammatory activity in Wistar albino rats. The group specific rats were treated for seven consecutive days and subjected to carrageenan induced paw oedema and cotton pellet implanted granuloma tissue formation tests at a dose of 8.64ml/kg (p.o). Both the test drugs have shown reduced paw volume during third and sixth hour readings and a moderate decrease in the granuloma tissue formation. CRP enzyme was found to be reduced significantly and a moderate elevation in white pulp of spleen from both the test groups were observed. The present findings suggest that both the drugs have moderate anti-inflammatory activity as ascertained by the comparative decrease in carrageenan induced paw volume, decreased granuloma tissue formation and normal histological profile of important organs.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.