Burn Wound Healing Potential of Rubia Cordifolia Linn on Wistar Albino Rats

Abstract

This study aimed to evaluate the wound healing property of Rubia cordifolia Linn in wistar albino rats in burn wound model where rats' dorsum were placed on wooden template and metallic screen. Both the template and screen were immersed in hot water bath for sixty seconds maintained at a temperature of 100 0 C. Animals were divided into three groups comprising of six animals each. Control group received the vehicle, standard group received silver sulfadiazine and test group were treated with paste of Rubia cordifolia as a topical application respectively. The topical application of test drug has shown significant wound contraction (**P<0.01) in comparison to normal control group. This was supported by the histopathological findings with good epithelialisation of cells when compared to normal control group.