This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. Abstract Background: Superficial fungal infections are often seen in day-to-day clinical practice, and their prevalence continues to rise worldwide. Over the years, a change in the pattern of dermatophytoses has been noted. Objectives: This study aimed to determine the epidemiologic profile of dermatophytes at the Department of Dermatology, University Hospital Jena, from 2007 to 2013. Methods: The retrospective study was carried out with a total of 4556 samples collected from 3607 patients suspected of superficial fungal infections during the 7-year study period. Results: Among the 3607 suspected patients, 1951 (54.09%) were men and 1656 (45.91%) were women. Of 4556 samples, 703 (15.43%) samples were positive for fungal culture, which included 585 (83.21%) dermatophytes and 118 (16.79%) nondermatophytes. Trichophyton (T.) rubrum was the most common isolated pathogen in 73.33% of the dermatophyte cases. Among dermatophyte-infected patients, menwere most likely to be affected (63.48%) as well as those of higher age (61 to 80). The most commonly affected areas were nails (33.16%) and feet (33%). T rubrum was recurrently isolated in several regions with exception of the scalp where M canis (58.33%) was the most frequently isolated pathogen. About 16.04% of cases had a history of treatment taken prior to sampling. The majority of the affected individuals did not have any prior animal contact (77.26%). T benhamiae was exclusively associated with contact to guinea pigs. Conclusion: Trichophyton rubrum was the most frequently isolated pathogen in several regions except the scalp. New dermatophyte species emerged with time especially T benhamiae. | 559 GAMAGE Et Al.

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Anamnese Ein zwei Tage altes neugeborenes Mädchen wurde in die dermatologische Klinik überwiesen wegen rasch aufgetretener livider Hautveränderungen. Das termingerecht geborene Kind war durch eine normale Vaginalgeburt mit einem Geburtsgewicht von 3,14 kg in einer Klinik der Maximalversorgung zur Welt gekommen und am folgenden Tag nach Hause entlassen worden. Am zweiten Lebenstag bemerkte die Mutter kleine schwarze Hautverfärbungen an Gesäß und Oberschenkeln, die im Laufe der Zeit immer größer wurden. An anderen Körperarealen traten ebenfalls neue Läsionen auf. Die Mutter stellte das Kind 18 Stunden später in der Kinderklinik vor. Das Mädchen wurde als Kind nicht konsanguiner Eltern geboren und hatte ein gesundes Geschwisterkind. Es gab keine Vorgeschichte für ähnliche Krankheiten oder postnatale Sterblichkeit in der Familie. Rasch progressive livid-schwarze Hautläsionen bei einem zwei Tage alten Neugeborenen Acute progressive purplish-black discolored skin lesions in a two-day-old newborn English online version on Wiley Online Library Diagnosequiz Abbildung 1 Mehrere große ekchymotische Plaques mit erythematösem Rand und zentraler Nekrose, die über Gesäß, Oberschenkel und Beine verteilt sind.

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