Background-Neutrophil formylpeptide receptors (FPRs) play an important role in bacterial recognition and chemotaxis. Defective FPR1 expression and impaired polymorphonuclear leukocyte (PMN) chemotaxis toward bacterial formylpeptides are associated with aggressive periodontitis (AP). The objective of this study was to determine whether single nucleotide polymorphisms (SNPs) in FPR1 are associated with AP.
Based on the results of this in vitro study, it may be concluded that ABM/P-15 enhanced the regenerative capacity of PDL by regulating specific gene expressions of cells during early wound healing.
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