96 nano-crystallization trials can be done with just (sub)-milligram amounts of an organic salt to directly yield single crystal structures.

The under-oil crystallization method was successfully adopted for the crystallization of organic salts. Compared with the previously reported vapour-diffusion-based nano-crystallization technique, the under-oil method generated single crystals of more different salts for all studied compounds.

The growth of single crystals of small molecules by thermal recrystallization of only a few milligrams of material has been studied for carbamazepine, para-aminobenzoic acid and vitamin B 12. High quality single crystals could be grown for carbamazepine and para-aminobenzoic acid within just six hours. Various solvents and concentrations were tested for their influence upon the growth of crystals.

Let pipetting robots set up nano crystallization trials of water-soluble metal complexes in order to obtain single crystals!

No abstract