K E Y W O R D S:
Results
Thirty-two fetuses (7%) were delivered within 48 h of the occurrence of ARED (25 absent, seven reversed end-diastolic flow). The remaining 10 fetuses (five absent, five reversed end-diastolic flow) were monitored for a median of 6.5 (range, 3-18) days before delivery. One infant died in the neonatal period and three during the first year of postnatal life (2-year survival 90%). The incidence of chronic lung disease was higher in the ARED Group than in Control Groups
Objectives Nuchal translucency (NT) screening increases antenatal detection of Down syndrome (DS) compared to maternal age-based screening. We wanted to determine if a change in policy for prenatal diagnosis would result in fewer babies born with DS.
Methods
Used in combination these methods lead to improvements in fetal morbidity and mortality. The aim of future research should be to minimize the risks of fetal morbidity and mortality further by the optimal timing of delivery. Better organization of healthcare systems may improve our ability to identify at-risk patients during pregnancy. There is potential to improve the specificity of fetal surveillance tests, e.g. better methods of biometry and amniotic volume estimation with three-dimensional ultrasound and measurements of subcutaneous tissue. Improved knowledge of fetal physiology can be gained from research on fetal circulation with Doppler studies. Computer analysis of the fetal heart rate can increase the specificity of that test, and artificial neural networks may enhance the ability to evaluate the optimal use of integrated testing.
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