Eighty-seven patients with neoplasm (57 cases), pancreatitis (28 cases), or benign biliary obstruction (2 cases) were treated with pyloric preserving pancreatectomy with two postoperative deaths, neither due to abdominal complications. About 50% of patients had delay in recovery of gastrointestinal function. Six and seven patients had clinically significant biliary and pancreatic fistulas, respectively, with some patients having both. Complications required 16 reoperations. Marginal ulcer was suggested by endoscopy or barium study in five patients, three of whom were successfully managed by a medical regimen. In the other two patients, exploration failed to demonstrate an ulcer or jejunitis. In most patients, long-term gastrointestinal function was judged to be excellent based on weight gain and lack of digestive symptoms. Pyloric function and gastric motility were evaluated by abdominal scanning using indium 111 and technetium 99m. Gastric emptying of liquids and solids was normal. Estimations of enterogastric reflux showed a moderate difference between normal subjects and pancreatectomy patients. Cancer-free survival was comparable to that after the standard Whipple procedure.
Five mothers of squirrel monkey infants isolated from other species members were muted by severence of their vocal cords during pregnancy. After delivery, mother infant pairs were brought up in an environment free of any species-specific auditory input. One of these infants underwent a deafening operation five days after birth. In addition, two infants grew up under normal conditions, i.e., exposed to species-specific vocalization. Supplemental data were acquired from six other infants, four of them normally raised and two handraised. Soundspectrograms were taken over a period up to six months in the case of the isolates and up to 17 months for the normal animals. Samples of this spectrographical material were analyzed with respect to the form of calls and to quantitative criteria, such as duration, starting frequency, mid-frequency, and end frequency of peep and cackle calls. Clear evidence is presented that the vocal repertoire of squirrel monkey infants raised under normal conditions and those raised in the absence of species-specific auditory input are virtually identical. Furthermore, comparison of the infants' vocalization with those of adult animals shows no significant differences.
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