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Adenylate kinase activity was measured in cerebrospinal fluid of healthy normal individuals and those having suffered from transitory ischaemic attacks (TIA). Normally, no adenylate kinase was present in cerebrospinal fluid. A slight but distinct activity was always registered in the 11 cases studied in connection with TL4. Cerebrospinal fluid of 2 patients was also analysed in a symptom-free interval (at least 2 weeks after the stroke) and no adenylate kinase activity was found.

Abstract. Dynamic lung function tests have been studied in apparently healthy men and women, who in essential respects may be considered as representative of the total population within the age range concerned. The results are compared with some previously reported “normal values”. Certain not unimportant differences exist in spite of essentially identical methods. It seems probable that these differences are due mainly to differences in the composition of the series compared; in previous investigations the selection of subjects does not appear to have been done on an adequate statistical basis.

Elevated adenylate kinase activities in serum and urine have been studied among patients suffering from myocardial infarction. 71% of the patients had clearly increased activities in serum already on admission to the hospital, i.e. about 12 hours after onset of symptoms and patients was 45%. A maximum peak value of the activity in serum was seen at 6 hours after admission to the hospital, i.e. about 12 hrs after onset of symptoms and the elevated enzyme activity value persisted for at least 12 hours after admission. The patients with the elevated adenylate kinase activity in serum were arbitrarily divided into three groups as regards activity. It was shown that the difference in activity of ASAT as well as LD of the high and low activity group was significant @<0.01). No such difference was established between these groups for ALAT, usually not being considered as a reliable test enzyme for myocardial infarction.