Machine learning models were built by using four different algorithms using Linear Regression, Regression Tree, Multi-Layer Perceptron, and Random Forest by 10-fold Cross-Validation method using the training set. The validity of the four different machine learning algorithms was verified by predicting the nuclide densities of 235 U, 238 U, 239 Pu, 241 Pu, 137 Cs, 244 Cm, and 254 Nd at different burn-up depths by enrichment and burn-up depth. The experimental results show that the Pearson Correlation Coefficients of the training sets of the four algorithms based on the 10-fold Cross-Validation method are all greater than 0.72, among which the evaluation coefficients of the models of Regression Tree and Random Forest are better than those of the Multi-Layer Perceptron and Linear Regression; however, the prediction based on the test set is found that the model of the Multi-Layer Perceptron predicts better than the other three models, and the average deviation is less than 1% and the average deviation is less than 3% for the Regression Tree and Random Forest algorithm model.
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